6FAB
 
 | | THREE-DIMENSIONAL STRUCTURE OF MURINE ANTI-P-AZOPHENYLARSONATE FAB 36-71. 1. X-RAY CRYSTALLOGRAPHY, SITE-DIRECTED MUTAGENESIS, AND MODELING OF THE COMPLEX WITH HAPTEN | | 分子名称: | IGG1-KAPPA 36-71 FAB (HEAVY CHAIN), IGG1-KAPPA 36-71 FAB (LIGHT CHAIN) | | 著者 | Strong, R.K, Rose, D.R, Petsko, G.A, Sharon, J, Margolies, M.N. | | 登録日 | 1991-01-17 | | 公開日 | 1993-01-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten.
Biochemistry, 30, 1991
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3CII
 | | Structure of NKG2A/CD94 bound to HLA-E | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen peptide, HLA class I histocompatibility antigen, ... | | 著者 | Strong, R.K, Kaiser, B.K, Pizarro, J.C. | | 登録日 | 2008-03-11 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (4.41 Å) | | 主引用文献 | Structural basis for NKG2A/CD94 recognition of HLA-E.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1KTL
 | | The human non-classical major histocompatibility complex molecule HLA-E | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | | 著者 | Holmes, M.A, Strong, R.K. | | 登録日 | 2002-01-16 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
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1KPR
 | | The human non-classical major histocompatibility complex molecule HLA-E | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | | 著者 | Holmes, M.A, Strong, R.K. | | 登録日 | 2002-01-02 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
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8CXC
 | | Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | | 分子名称: | 3F2 Antibody heavy chain, 3F2 Antibody light chain, Mesothelin, ... | | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | | 登録日 | 2022-05-20 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4.31 Å) | | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
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8CZ8
 | | Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | | 分子名称: | Mesothelin, cleaved form, SULFATE ION, ... | | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | | 登録日 | 2022-05-24 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
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8CYH
 | | Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, A12 antibody heavy chain, A12 antibody light chain, ... | | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | | 登録日 | 2022-05-23 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
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7SNC
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7SND
 | | Pacifastin related protease inhibitors | | 分子名称: | GLYCEROL, PHOSPHATE ION, Pacifastin-related peptide | | 著者 | Gewe, M.M, Strong, R.K. | | 登録日 | 2021-10-27 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
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4R0L
 | | Anti-canine CD28 antibody, 1C6, bound canine CD28 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gewe, M.M, Strong, R.K. | | 登録日 | 2014-07-31 | | 公開日 | 2015-07-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Anti-CD28 Antibody-Initiated Cytokine Storm in Canines.
Transplant Direct, 1, 2015
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5JR8
 | | Disposal of Iron by a Mutant form of Siderocalin NGAL | | 分子名称: | GLYCEROL, Neutrophil gelatinase-associated lipocalin, PHOSPHATE ION | | 著者 | Rupert, P.B, Strong, R.K, Barasch, J, Hollman, M, Deng, R, Hod, E.A, Abergel, R, Allred, B, Xu, K, Darrah, S, Tekabe, Y, Perlstein, A, Bruck, E, Stauber, J, Corbin, K, Buchen, C, Slavkovich, V, Graziano, J, Spitalnik, S, Qiu, A. | | 登録日 | 2016-05-05 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Disposal of iron by a mutant form of lipocalin 2.
Nat Commun, 7, 2016
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5KIC
 | | Long-sought stabilization of berkelium(IV) in solution: An anomaly within the heavy actinide series | | 分子名称: | CALIFORNIUM ION, CHLORIDE ION, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ... | | 著者 | Rupert, P.B, Strong, R.K. | | 登録日 | 2016-06-16 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Chelation and stabilization of berkelium in oxidation state +IV.
Nat Chem, 9, 2017
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5KID
 | | Tightening the Recognition of Tetravalent Zr and Th Complexes by the Siderophore-Binding Mammalian Protein Siderocalin for Theranostic Applications | | 分子名称: | CHLORIDE ION, GLYCEROL, N,N'-(butane-1,4-diyl)bis(N-{3-[(2,3-dihydroxybenzene-1-carbonyl)amino]propyl}-2,3-dihydroxybenzamide), ... | | 著者 | Rupert, P.B, Strong, R.K. | | 登録日 | 2016-06-16 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms.
Inorg Chem, 55, 2016
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5KHP
 | | Tightening the Recognition of Tetravalent Zr and Th Complexes by the Siderophore-Binding Mammalian Protein Siderocalin for Theranostic Applications | | 分子名称: | GLYCEROL, N,N'-(butane-1,4-diyl)bis(N-{3-[(2,3-dihydroxybenzene-1-carbonyl)amino]propyl}-2,3-dihydroxybenzamide), Neutrophil gelatinase-associated lipocalin, ... | | 著者 | Rupert, P.B, Strong, R.K. | | 登録日 | 2016-06-15 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms.
Inorg Chem, 55, 2016
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7SGQ
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7SLT
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7SOH
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3OMZ
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3RU8
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3S26
 | | Crystal Structure of Murine Siderocalin (Lipocalin 2, 24p3) | | 分子名称: | Neutrophil gelatinase-associated lipocalin, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Correnti, C, Bandaranayake, A.D, Strong, R.K. | | 登録日 | 2011-05-16 | | 公開日 | 2011-09-28 | | 最終更新日 | 2021-03-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors.
Nucleic Acids Res., 39, 2011
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3SAO
 | | The Siderocalin Ex-FABP functions through dual ligand specificities | | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 2,3-DIHYDROXY-BENZOIC ACID, Extracellular fatty acid-binding protein, ... | | 著者 | Correnti, C, Strong, R.K, Clifton, M.C. | | 登録日 | 2011-06-03 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Galline Ex-FABP Is an Antibacterial Siderocalin and a Lysophosphatidic Acid Sensor Functioning through Dual Ligand Specificities.
Structure, 19, 2011
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6O5D
 | | PYOCHELIN | | 分子名称: | GLYCEROL, Neutrophil gelatinase-associated lipocalin, SULFATE ION | | 著者 | Rupert, P.B, Strong, R.K, Clifton, M.C, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2019-03-01 | | 公開日 | 2019-09-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands.
J Struct Biol X, 2, 2019
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6OKD
 | | Crystal Structure of human transferrin receptor in complex with a cystine-dense peptide | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Finton, K.A.K, Rupert, P.B, Strong, R.K. | | 登録日 | 2019-04-12 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules.
J.Mol.Biol., 432, 2020
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3T43
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6OKE
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