3CX8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cx8 by Molmil](/molmil-images/mine/3cx8) | |
1IAP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1iap by Molmil](/molmil-images/mine/1iap) | |
3CX6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cx6 by Molmil](/molmil-images/mine/3cx6) | |
3CX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cx7 by Molmil](/molmil-images/mine/3cx7) | |
1XHM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xhm by Molmil](/molmil-images/mine/1xhm) | The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, SIGK Peptide | Authors: | Davis, T.L, Bonacci, T.M, Smrcka, A.V, Sprang, S.R. | Deposit date: | 2004-09-20 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits. Biochemistry, 44, 2005
|
|
1BOF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bof by Molmil](/molmil-images/mine/1bof) | GI-ALPHA-1 BOUND TO GDP AND MAGNESIUM | Descriptor: | GI ALPHA 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Coleman, D.E, Sprang, S.R. | Deposit date: | 1998-08-04 | Release date: | 1999-01-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment. Biochemistry, 37, 1998
|
|
3C16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c16 by Molmil](/molmil-images/mine/3c16) | |
3C14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c14 by Molmil](/molmil-images/mine/3c14) | |
1NCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ncf by Molmil](/molmil-images/mine/1ncf) | |
6AU4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6au4 by Molmil](/molmil-images/mine/6au4) | Crystal structure of the major quadruplex formed in the human c-MYC promoter | Descriptor: | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), POTASSIUM ION | Authors: | Stump, S, Mou, T.C, Sprang, S.R, Natale, N.R, Beall, H.D. | Deposit date: | 2017-08-30 | Release date: | 2018-09-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene. PLoS ONE, 13, 2018
|
|
3C15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c15 by Molmil](/molmil-images/mine/3c15) | |
4MU8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mu8 by Molmil](/molmil-images/mine/4mu8) | Crystal structure of an oxidized form of yeast iso-1-cytochrome c at pH 8.8 | Descriptor: | Cytochrome c iso-1, GLYCEROL, HEME C, ... | Authors: | McClelland, L.J, Mou, T.-C, Jeakins-Cooley, M.E, Sprang, S.R, Bowler, B.E. | Deposit date: | 2013-09-20 | Release date: | 2014-06-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a mitochondrial cytochrome c conformer competent for peroxidase activity. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
6D8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d8x by Molmil](/molmil-images/mine/6d8x) | PPAR gamma LBD complexed with the agonist GW1929 | Descriptor: | (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CITRATE ANION, GLYCEROL, ... | Authors: | Mou, T.C, Chrisman, I.M, Hughes, T.S, Sprang, S.R. | Deposit date: | 2018-04-27 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | PPAR gamma LBD complexed with the agonist GW1929 To Be Published
|
|
6DBH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dbh by Molmil](/molmil-images/mine/6dbh) | Crystal structure of PPAR gamma in complex with NMP422 | Descriptor: | 4-{2-[(2,3-dioxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)sulfanyl]ethyl}benzoic acid, CHLORIDE ION, Peroxisome proliferator-activated receptor gamma | Authors: | Mou, T.C, Chrisman, I.M, Hughes, T.S, Sprang, S.R. | Deposit date: | 2018-05-03 | Release date: | 2019-05-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Crystal structure of PPAR gamma in complex with NMP422 To Be Published
|
|
6DCU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dcu by Molmil](/molmil-images/mine/6dcu) | |
5I56
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5i56 by Molmil](/molmil-images/mine/5i56) | Agonist-bound GluN1/GluN2A agonist binding domains with TCN201 | Descriptor: | GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ... | Authors: | Mou, T.-C, Sprang, S.R, Hansen, K.B. | Deposit date: | 2016-02-14 | Release date: | 2016-09-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. Neuron, 91, 2016
|
|
1IK7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ik7 by Molmil](/molmil-images/mine/1ik7) | Crystal Structure of the Uncomplexed Pelle Death Domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PROBABLE SERINE/THREONINE-PROTEIN KINASE Pelle | Authors: | Xiao, T, Gardner, K.H, Sprang, S.R. | Deposit date: | 2001-05-02 | Release date: | 2002-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cosolvent-induced transformation
of a death domain tertiary structure Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1TNF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tnf by Molmil](/molmil-images/mine/1tnf) | |
5DEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dez by Molmil](/molmil-images/mine/5dez) | Crystal structure of AcMNPV Chitinase A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ac-ChiA, ... | Authors: | Mou, T.-C, Sprang, S.R. | Deposit date: | 2015-08-26 | Release date: | 2016-09-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of AcMNPV Chitinase A To Be Published
|
|
6OVD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ovd by Molmil](/molmil-images/mine/6ovd) | Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-ACEPC | Descriptor: | (3S,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(3-ethylphenyl)pyrazolidine-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ... | Authors: | Syrenne, J.T, Mou, T.C, Tamborini, L, Pinto, A, Sprang, S.R, Hansen, K.B. | Deposit date: | 2019-05-07 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-ACEPC To Be Published
|
|
6OVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ove by Molmil](/molmil-images/mine/6ove) | Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC | Descriptor: | (3R,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(4-propylphenyl)pyrazolidine-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ... | Authors: | Syrenne, J.T, Mou, T.C, Tamborini, L, Pinto, A, Sprang, S.R, Hansen, K.B. | Deposit date: | 2019-05-07 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-ACEPC To Be Published
|
|
5T7H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5t7h by Molmil](/molmil-images/mine/5t7h) | Crystal structure of dimeric yeast iso-1-cytochrome C with CYMAL6 | Descriptor: | 6-cyclohexylhexan-1-ol, Cytochrome c iso-1, HEME C, ... | Authors: | Mcclelland, L, Mou, T.C, Sprang, S.R, Bowler, B.E. | Deposit date: | 2016-09-05 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons. J. Am. Chem. Soc., 138, 2016
|
|
1YBT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ybt by Molmil](/molmil-images/mine/1ybt) | MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE, RV1900C CHD | Descriptor: | hydrolase, alpha/beta hydrolase fold family | Authors: | Sinha, S.C, Wetterer, M, Sprang, S.R, Schultz, J.E, Linder, J.U. | Deposit date: | 2004-12-21 | Release date: | 2005-02-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c. Embo J., 24, 2005
|
|
1YBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ybu by Molmil](/molmil-images/mine/1ybu) | Mycobacterium tuberculosis adenylyl cyclase Rv1900c CHD, in complex with a substrate analog. | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION, lipJ | Authors: | Sinha, S.C, Wetterer, M, Sprang, S.R, Schultz, J.E, Linder, J.U. | Deposit date: | 2004-12-21 | Release date: | 2005-02-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c. Embo J., 24, 2005
|
|
3KZ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kz1 by Molmil](/molmil-images/mine/3kz1) | Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ... | Authors: | Chen, Z, Sternweis, P.C, Sprang, S.R. | Deposit date: | 2009-12-07 | Release date: | 2010-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation. J.Biol.Chem., 285, 2010
|
|