3CX8

Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GTP-gamma-S

Summary for 3CX8

Entry DOI	10.2210/pdb3cx8/pdb
Related	1SHZ 3CX6 3CX7
Descriptor	Guanine nucleotide-binding protein alpha-13 subunit, Rho guanine nucleotide exchange factor 11, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	signal transduction, protein complex, gtp-binding, lipoprotein, membrane, nucleotide-binding, palmitate, phosphoprotein, transducer, coiled coil, cytoplasm, gtpase activation, guanine-nucleotide releasing factor, signaling protein
Biological source	Mus musculus (Mouse) More
Cellular location	Membrane ; Lipid-anchor : P27601 Cytoplasm : Q9ES67
Total number of polymer chains	2
Total formula weight	63630.42
Authors	Sprang, S.R.,Chen, Z. (deposition date: 2008-04-23, release date: 2008-10-28, Last modification date: 2023-08-30)
Primary citation	Chen, Z.,Singer, W.D.,Danesh, S.M.,Sternweis, P.C.,Sprang, S.R. Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF. Structure, 16:1532-1543, 2008 Cited by PubMed: 18940608 DOI: 10.1016/j.str.2008.07.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation