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3CX8

Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GTP-gamma-S

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein alpha-13 subunitpolymer33839743.51UniProt (P27601)
Pfam (PF00503)
Mus musculus (Mouse)G alpha-13
2B
(B)
Rho guanine nucleotide exchange factor 11polymer20323323.31UniProt (Q9ES67)
Pfam (PF09128)
Rattus norvegicus (Rat)RhoGEF glutamate transport modulator GTRAP48
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATEnon-polymer539.21Chemie (GSP)
5E, F
(A, B)
waterwater18.0298Chemie (HOH)
Sequence modifications
A: 41 - 377 (UniProt: P27601)
PDBExternal DatabaseDetails
Gly 40-expression tag
B: 307 - 508 (UniProt: Q9ES67)
PDBExternal DatabaseDetails
Gly 306-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63066.9
Non-Polymers*Number of molecules2
Total formula weight563.6
All*Total formula weight63630.4
*Water molecules are not included.

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PDB entries from 2025-07-30

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