6AU4
Crystal structure of the major quadruplex formed in the human c-MYC promoter
Summary for 6AU4
Entry DOI | 10.2210/pdb6au4/pdb |
Descriptor | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), POTASSIUM ION (3 entities in total) |
Functional Keywords | oncogene, quadruplex, c-myc, promoter, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 14251.61 |
Authors | Stump, S.,Mou, T.C.,Sprang, S.R.,Natale, N.R.,Beall, H.D. (deposition date: 2017-08-30, release date: 2018-09-12, Last modification date: 2023-10-04) |
Primary citation | Stump, S.,Mou, T.C.,Sprang, S.R.,Natale, N.R.,Beall, H.D. Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene. PLoS ONE, 13:e0205584-e0205584, 2018 Cited by PubMed: 30312328DOI: 10.1371/journal.pone.0205584 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
Download full validation report