6D8X

PPAR gamma LBD complexed with the agonist GW1929

Summary for 6D8X

• Entry DOI: 10.2210/pdb6d8x/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CITRATE ANION, ... (6 entities in total)
• Functional Keywords: nuclear receptor, transcription factor, super agonist, ligand binding domain, dna binding protein, dna binding protein-agonist complex, dna binding protein/agonist
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 34998.15

Authors

Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. (deposition date: 2018-04-27, release date: 2019-05-01, Last modification date: 2023-10-04)

• Primary citation: Chrisman, I.M.,Mou, T.C.,Sprang, S.R.,Hughes, T.S.; PPAR gamma LBD complexed with the agonist GW1929; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)