6D8X
PPAR gamma LBD complexed with the agonist GW1929
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 297 | 34152.4 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (A) | (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid | non-polymer | 495.6 | 1 | Chemie (EDK) | |||
| 3 | C (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 4 | D, E, F (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | H (A) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Met 181 | - | initiating methionine |
| Ala 182 | - | expression tag |
| His 183 | - | expression tag |
| His 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| Val 189 | - | expression tag |
| Asp 190 | - | expression tag |
| Asp 191 | - | expression tag |
| Asp 192 | - | expression tag |
| Asp 193 | - | expression tag |
| Lys 194 | - | expression tag |
| Met 195 | - | expression tag |
| Glu 196 | - | expression tag |
| Asn 197 | - | expression tag |
| Leu 198 | - | expression tag |
| Tyr 199 | - | expression tag |
| Phe 200 | - | expression tag |
| Gln 201 | - | expression tag |
| Gly 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34152.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 845.7 | |
| All* | Total formula weight | 34998.2 |
