Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue EDK A 501 |
| Chain | Residue |
| A | PHE282 |
| A | MET364 |
| A | HIS449 |
| A | TYR473 |
| A | HOH703 |
| A | HOH706 |
| A | GLY284 |
| A | CYS285 |
| A | SER289 |
| A | HIS323 |
| A | TYR327 |
| A | LEU330 |
| A | ILE341 |
| A | PHE363 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue FLC A 502 |
| Chain | Residue |
| A | LYS216 |
| A | ARG234 |
| A | THR238 |
| A | ASN375 |
| A | HOH606 |
| A | HOH640 |
| A | HOH644 |
| A | HOH690 |
| A | HOH726 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 503 |
| Chain | Residue |
| A | ARG443 |
| A | GLN444 |
| A | NA504 |
| A | HOH655 |
| A | HOH763 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 504 |
| Chain | Residue |
| A | THR440 |
| A | GLN444 |
| A | NA503 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 505 |
| Chain | Residue |
| A | LYS457 |
| A | TYR473 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | PRO227 |
| A | LEU228 |
| A | ARG288 |
| A | GLU295 |
| A | HOH601 |
| A | HOH633 |
| A | HOH717 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 265 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Motif: {"description":"9aaTAD","evidences":[{"source":"PubMed","id":"30468856","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9744270","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PRG","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36737649","evidenceCode":"ECO:0000269"}]} |
