6DBH
Crystal structure of PPAR gamma in complex with NMP422
Summary for 6DBH
Entry DOI | 10.2210/pdb6dbh/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, 4-{2-[(2,3-dioxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)sulfanyl]ethyl}benzoic acid, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | nuclear receptor, transcription factor, super agonist, ligand binding domain, coactivator, med1, dna binding protein, dna binding protein-agonist complex, dna binding protein/agonist |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 69206.17 |
Authors | Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. (deposition date: 2018-05-03, release date: 2019-05-08, Last modification date: 2023-10-04) |
Primary citation | Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. Crystal structure of PPAR gamma in complex with NMP422 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.597 Å) |
Structure validation
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