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1XHM

The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer

Summary for 1XHM
Entry DOI10.2210/pdb1xhm/pdb
Related1A0R 1GG2 1OMW 1TBG
DescriptorGuanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, SIGK Peptide, ... (4 entities in total)
Functional Keywordswd40 repeat, beta-propeller, protein-peptide complex, signaling protein
Biological sourceBos taurus (cattle)
More
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212
Total number of polymer chains3
Total formula weight47795.87
Authors
Davis, T.L.,Bonacci, T.M.,Smrcka, A.V.,Sprang, S.R. (deposition date: 2004-09-20, release date: 2005-08-09, Last modification date: 2023-08-23)
Primary citationDavis, T.L.,Bonacci, T.M.,Sprang, S.R.,Smrcka, A.V.
Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits.
Biochemistry, 44:10593-10604, 2005
Cited by
PubMed: 16060668
DOI: 10.1021/bi050655i
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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