1OMW

Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits

Summary for 1OMW

Entry DOI	10.2210/pdb1omw/pdb
Descriptor	G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, ... (4 entities in total)
Functional Keywords	wd-40 repeat, transferase
Biological source	Bos taurus (cattle) More
Cellular location	Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212
Total number of polymer chains	3
Total formula weight	125573.51
Authors	Lodowski, D.T.,Pitcher, J.A.,Capel, W.D.,Lefkowitz, R.J.,Tesmer, J.J.G. (deposition date: 2003-02-26, release date: 2003-06-03, Last modification date: 2023-08-16)
Primary citation	Lodowski, D.T.,Pitcher, J.A.,Capel, W.D.,Lefkowitz, R.J.,Tesmer, J.J.G. Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma Science, 300:1256-1262, 2003 Cited by PubMed: 12764189 DOI: 10.1126/science.1082348 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation