6DCU
Crystal structure of PPAR gamma co-crystallized with nTZDpa
Summary for 6DCU
Entry DOI | 10.2210/pdb6dcu/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, 5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID (2 entities in total) |
Functional Keywords | nuclear receptor, transcription factor, super agonist, ligand binding domain, coactivator, med1, dna binding protein, dna binding protein-agonist complex, dna binding protein/agonist |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 70094.69 |
Authors | Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. (deposition date: 2018-05-08, release date: 2019-05-15, Last modification date: 2023-10-11) |
Primary citation | Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. Crystal structure of PPAR gamma in complex with NMP422 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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