6DCU

Crystal structure of PPAR gamma co-crystallized with nTZDpa

Summary for 6DCU

• Entry DOI: 10.2210/pdb6dcu/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, 5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID (2 entities in total)
• Functional Keywords: nuclear receptor, transcription factor, super agonist, ligand binding domain, coactivator, med1, dna binding protein, dna binding protein-agonist complex, dna binding protein/agonist
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 70094.69

Authors

Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. (deposition date: 2018-05-08, release date: 2019-05-15, Last modification date: 2023-10-11)

• Primary citation: Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R.; Crystal structure of PPAR gamma in complex with NMP422; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.95 Å)