8PR3
 
 | | Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1 | | Descriptor: | C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... | | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | Deposit date: | 2023-07-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
|
|
8PQZ
 | | Cytoplasmic dynein-1 A1/A2 motor domains bound to LIS1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | Deposit date: | 2023-07-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
|
|
8PR5
 | | Structure of the autoinhibited dynactin p150glued projection | | Descriptor: | Dynactin subunit 1 | | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | Deposit date: | 2023-07-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (8.6 Å) | | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
|
|
8PQW
 | | Cytoplasmic dynein-1 motor domain bound to dynactin-p150glued and LIS1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | Deposit date: | 2023-07-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
|
|
8PR1
 | | Cytoplasmic dynein-B heavy chain bound to IC-LC tower | | Descriptor: | Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein 1 light intermediate chain 2, ... | | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | Deposit date: | 2023-07-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (8.2 Å) | | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
|
|
3CPZ
 | | Crystal structure of VAR2CSA DBL3x domain in the presence of dodecasaccharide of CSA | | Descriptor: | Erythrocyte membrane protein 1, SULFATE ION | | Authors: | Singh, K, Gittis, A.G, Nguyen, P, Gowda, D.C, Miller, L.H, Garboczi, D.N. | | Deposit date: | 2008-04-01 | | Release date: | 2008-09-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.
Nat.Struct.Mol.Biol., 15, 2008
|
|
3CML
 | | Crystal Structure of the DBL3x domain of the Plasmodium falcipurum VAR2CSA protein | | Descriptor: | Erythrocyte membrane protein 1 | | Authors: | Singh, K, Gittis, A.G, Nguyen, P, Gowda, D.C, Miller, L.H, Garboczi, D.N. | | Deposit date: | 2008-03-23 | | Release date: | 2008-09-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.
Nat.Struct.Mol.Biol., 15, 2008
|
|
6OHG
 | | Structure of Plasmodium falciparum vaccine candidate Pfs230D1M in complex with the Fab of a transmission blocking antibody | | Descriptor: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 4F12 Heavy chain, ... | | Authors: | Garboczi, D.N, Singh, K, Gittis, A.G. | | Deposit date: | 2019-04-05 | | Release date: | 2020-06-17 | | Last modified: | 2021-03-31 | | Method: | X-RAY DIFFRACTION (2.385 Å) | | Cite: | Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins.
Commun Biol, 3, 2020
|
|
7NHT
 | | Akirin2 bound human proteasome | | Descriptor: | Akirin-2, POTASSIUM ION, Proteasome subunit alpha type-1, ... | | Authors: | Singh, K, Brunner, H, Grishkovskaya, I, de Almeida, M, Hinterndorfer, M, Zuber, J, Haselbach, D. | | Deposit date: | 2021-02-11 | | Release date: | 2021-09-01 | | Last modified: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature, 599, 2021
|
|
7TXW
 | | Crystal structure of the complex of the malaria sexual stage protein and vaccine target Pfs25 with the Fab fragment of a transmission blocking antibody 1G2 | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ETHANOL, ... | | Authors: | Singh, K, Gittis, A.G, Garboczi, D.N. | | Deposit date: | 2022-02-10 | | Release date: | 2023-04-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles.
Npj Vaccines, 8, 2023
|
|
8E1A
 | | Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors | | Descriptor: | 1,2-ETHANEDIOL, 4-[4-(3-fluoro-2-methoxyphenyl)-1,3-thiazol-2-yl]morpholine, Androgen receptor | | Authors: | Lallous, N, Li, H, Radaeva, M, Dalal, K, Leblanc, E, Ban, F, Ciesielski, F, Chow, B, Morin, M, Singh, K, Rennie, P.S, Cherkasov, A. | | Deposit date: | 2022-08-10 | | Release date: | 2022-09-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors.
Cells, 11, 2022
|
|
3LO5
 | | Crystal Structure of the dominant negative S17N mutant of Ras | | Descriptor: | CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Nassar, N, Singh, K, Garcia-Diaz, M. | | Deposit date: | 2010-02-03 | | Release date: | 2010-03-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.568 Å) | | Cite: | Structure of the Dominant Negative S17N Mutant of Ras
Biochemistry, 49, 2010
|
|
1KC5
 | | CRYSTAL STRUCTURE OF ANTIBODY PC287 IN COMPLEX WITH PS1 PEPTIDE | | Descriptor: | PC287 Immunoglobulin, PS1 peptide | | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V, Salunke, D.M. | | Deposit date: | 2001-11-07 | | Release date: | 2002-07-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
|
|
1KCS
 | | CRYSTAL STRUCTURE OF ANTIBODY PC282 IN COMPLEX WITH PS1 PEPTIDE | | Descriptor: | PC282 IMMUNOGLOBULIN, PS1 peptide | | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V.S, Salunke, D.M. | | Deposit date: | 2001-11-11 | | Release date: | 2002-05-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
|
|
1KCU
 | | CRYSTAL STRUCTURE OF ANTIBODY PC287 | | Descriptor: | PC287 IMMUNOGLOBULIN | | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V.S, Salunke, D.M. | | Deposit date: | 2001-11-11 | | Release date: | 2002-05-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
|
|
1KCV
 | | Crystal structure of antibody pc282 | | Descriptor: | PC282 IMMUNOGLOBULIN | | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V, Salunke, D.M. | | Deposit date: | 2001-11-11 | | Release date: | 2002-05-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
|
|
4LVC
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenosine | | Descriptor: | ACETATE ION, ADENOSINE, AMMONIUM ION, ... | | Authors: | Manszewski, T, Singh, K, Imiolczyk, B, Jaskolski, M. | | Deposit date: | 2013-07-26 | | Release date: | 2014-07-30 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii.
Acta Crystallogr.,Sect.D, 71, 2015
|
|
1Z27
 | | Crystal structure of Native Pvs25, an ookinete protein from Plasmodium vivax. | | Descriptor: | ookinete surface protein Pvs25 | | Authors: | Saxena, A.K, Singh, K, Su, H.P, Klein, M.M, Stowers, A.W, Saul, A.J, Long, C.A, Garboczi, D.N. | | Deposit date: | 2005-03-07 | | Release date: | 2005-12-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
Nat.Struct.Mol.Biol., 13, 2006
|
|
1Z3G
 | | Crystal structure of complex between Pvs25 and Fab fragment of malaria transmission blocking antibody 2A8 | | Descriptor: | 2A8 Fab Heavy Chain, 2A8 Fab Light Chain, ookinete surface protein Pvs25 | | Authors: | Saxena, A.K, Singh, K, Su, H.P, Klein, M.M, Stowers, A.W, Saul, A.J, Long, C.A, Garboczi, D.N. | | Deposit date: | 2005-03-12 | | Release date: | 2005-12-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
Nat.Struct.Mol.Biol., 13, 2006
|
|
1Z1Y
 | | Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax | | Descriptor: | YTTERBIUM (III) ION, ookinete surface protein Pvs25 | | Authors: | Saxena, A.K, Singh, K, Su, H.P, Klein, M.M, Stowers, A.W, Saul, A.J, Long, C.A, Garboczi, D.N. | | Deposit date: | 2005-03-07 | | Release date: | 2005-12-06 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
Nat.Struct.Mol.Biol., 13, 2006
|
|
1KCR
 | | CRYSTAL STRUCTURE OF ANTIBODY PC283 IN COMPLEX WITH PS1 PEPTIDE | | Descriptor: | PC283 IMMUNOGLOBULIN, PS1 peptide | | Authors: | Nair, D.T, Singh, K, Sahu, N, Rao, K.V.S, Salunke, D.M. | | Deposit date: | 2001-11-11 | | Release date: | 2002-05-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of an antibody bound to an immunodominant peptide epitope: novel features in peptide-antibody recognition.
J.Immunol., 165, 2000
|
|
6VU1
 | |
6VVJ
 | | Cap1G-TPUA | | Descriptor: | RNA (130-MER) | | Authors: | Summers, M.F, Brown, J.D. | | Deposit date: | 2020-02-18 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-06 | | Method: | SOLUTION NMR | | Cite: | Structural basis for transcriptional start site control of HIV-1 RNA fate.
Science, 368, 2020
|
|
4WYL
 | | Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus | | Descriptor: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E. | | Deposit date: | 2014-11-17 | | Release date: | 2015-05-06 | | Last modified: | 2015-06-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
|
|
4X2B
 | |
