8E1A

Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors

Replaces:  4U4K

Summary for 8E1A

• Entry DOI: 10.2210/pdb8e1a/pdb
• Descriptor: Androgen receptor, 4-[4-(3-fluoro-2-methoxyphenyl)-1,3-thiazol-2-yl]morpholine, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: androgen receptor, agonist, antagonist, hormone receptor, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 32684.09

Authors

Lallous, N.,Li, H.,Radaeva, M.,Dalal, K.,Leblanc, E.,Ban, F.,Ciesielski, F.,Chow, B.,Morin, M.,Singh, K.,Rennie, P.S.,Cherkasov, A. (deposition date: 2022-08-10, release date: 2022-09-14, Last modification date: 2024-04-03)

• Primary citation: Radaeva, M.,Li, H.,LeBlanc, E.,Dalal, K.,Ban, F.,Ciesielski, F.,Chow, B.,Morin, H.,Awrey, S.,Singh, K.,Rennie, P.S.,Lallous, N.,Cherkasov, A.; Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors.; Cells, 11:-, 2022; PubMed: 36139361; DOI: 10.3390/cells11182785

Experimental method

X-RAY DIFFRACTION (1.2 Å)