8PQZ

Cytoplasmic dynein-1 A1/A2 motor domains bound to LIS1

Summary for 8PQZ

• Entry DOI: 10.2210/pdb8pqz/pdb
• EMDB information: 17829
• Descriptor: Cytoplasmic dynein 1 heavy chain 1, Platelet-activating factor acetylhydrolase IB subunit beta, Dynactin subunit 1, ... (7 entities in total)
• Functional Keywords: dynein, aaa-atpase, lis1, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 1770960.19

Authors

Singh, K.,Lau, C.K.,Manigrasso, G.,Gassmann, R.,Carter, A.P. (deposition date: 2023-07-12, release date: 2024-03-27, Last modification date: 2024-04-10)

• Primary citation: Singh, K.,Lau, C.K.,Manigrasso, G.,Gama, J.B.,Gassmann, R.,Carter, A.P.; Molecular mechanism of dynein-dynactin complex assembly by LIS1.; Science, 383:eadk8544-eadk8544, 2024; PubMed: 38547289; DOI: 10.1126/science.adk8544

Experimental method

ELECTRON MICROSCOPY (5.5 Å)