Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7MK8
DownloadVisualize
BU of 7mk8 by Molmil
Crystal structure of a surface mutant of human fetal-specific CYP3A7 bound to dithiothreitol
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Isoform 2 of Cytochrome P450 3A7, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Sevrioukova, I.F.
登録日2021-04-21
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Basis for the Diminished Ligand Binding and Catalytic Ability of Human Fetal-Specific CYP3A7.
Int J Mol Sci, 22, 2021
3UA1
DownloadVisualize
BU of 3ua1 by Molmil
Crystal structure of the cytochrome P4503A4-bromoergocryptine complex
分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, bromoergocryptine
著者Sevrioukova, I.F, Poulos, T.L.
登録日2011-10-20
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and Mechanistic Insights into the Interaction of Cytochrome P4503A4 with Bromoergocryptine, a Type I Ligand.
J.Biol.Chem., 287, 2012
3GD4
DownloadVisualize
BU of 3gd4 by Molmil
Crystal structure of the reduced, NAD-bound form of murine apoptosis inducing factor
分子名称: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Sevrioukova, I.F.
登録日2009-02-23
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Redox-linked conformational dynamics in apoptosis-inducing factor
J.Mol.Biol., 390, 2009
3TJS
DownloadVisualize
BU of 3tjs by Molmil
Crystal Structure of the complex between human cytochrome P450 3A4 and desthiazolylmethyloxycarbonyl ritonavir
分子名称: Cytochrome P450 3A4, N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F, Poulos, T.L.
登録日2011-08-24
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Interaction of human cytochrome P4503A4 with ritonavir analogs.
Arch.Biochem.Biophys., 520, 2012
3GD3
DownloadVisualize
BU of 3gd3 by Molmil
Crystal structure of a naturally folded murine apoptosis inducing factor
分子名称: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE
著者Sevrioukova, I.F.
登録日2009-02-23
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Redox-linked conformational dynamics in apoptosis-inducing factor
J.Mol.Biol., 390, 2009
3LB8
DownloadVisualize
BU of 3lb8 by Molmil
Crystal structure of the covalent putidaredoxin reductase-putidaredoxin complex
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, Putidaredoxin, ...
著者Sevrioukova, I.F.
登録日2010-01-07
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the putidaredoxin reductase x putidaredoxin electron transfer complex.
J.Biol.Chem., 285, 2010
5A1R
DownloadVisualize
BU of 5a1r by Molmil
Crystal structure of cytochrome P450 3A4 bound to progesterone
分子名称: CYTOCHROME P450 3A4, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F, Poulos, T.L.
登録日2015-05-04
公開日2015-06-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Anion-Dependent Stimulation of Cyp3A4 Monooxygenase
Biochemistry, 54, 2015
8SO2
DownloadVisualize
BU of 8so2 by Molmil
Human CYP3A4 bound to a substrate
分子名称: CAFFEINE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F.
登録日2023-04-28
公開日2023-08-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding.
J.Biol.Chem., 299, 2023
8SO1
DownloadVisualize
BU of 8so1 by Molmil
Human CYP3A4 bound to three caffeine molecules
分子名称: CAFFEINE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F.
登録日2023-04-28
公開日2023-08-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding.
J.Biol.Chem., 299, 2023
1BVY
DownloadVisualize
BU of 1bvy by Molmil
COMPLEX OF THE HEME AND FMN-BINDING DOMAINS OF THE CYTOCHROME P450(BM-3)
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, PROTEIN (CYTOCHROME P450 BM-3), ...
著者Sevrioukova, I.F, Li, H, Zhang, H, Peterson, J.A, Poulos, T.L.
登録日1998-09-21
公開日1999-02-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structure of a cytochrome P450-redox partner electron-transfer complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
3NXU
DownloadVisualize
BU of 3nxu by Molmil
Crystal structure of human cytochrome P4503A4 bound to an inhibitor ritonavir
分子名称: Cytochrome P450 3A4, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Sevrioukova, I.F, Poulos, T.L.
登録日2010-07-14
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir.
Proc.Natl.Acad.Sci.USA, 107, 2010
4K9V
DownloadVisualize
BU of 4k9v by Molmil
Complex of CYP3A4 with a desoxyritonavir analog
分子名称: 1,3-thiazol-5-ylmethyl [(3S,6S)-6-{[N-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-seryl]amino}octan-3-yl]carbamate, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F, Poulos, T.L.
登録日2013-04-21
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Dissecting Cytochrome P450 3A4-Ligand Interactions Using Ritonavir Analogues.
Biochemistry, 52, 2013
4K9X
DownloadVisualize
BU of 4k9x by Molmil
Complex of human CYP3A4 with a desoxyritonavir analog
分子名称: 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-methylbutanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F, Poulos, T.L.
登録日2013-04-21
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Dissecting Cytochrome P450 3A4-Ligand Interactions Using Ritonavir Analogues.
Biochemistry, 52, 2013
4K9U
DownloadVisualize
BU of 4k9u by Molmil
Complex of human CYP3A4 with a desoxyritonavir analog
分子名称: Cytochrome P450 3A4, N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-[(2S,5S)-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-D-valinamide, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F, Poulos, T.L.
登録日2013-04-21
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Dissecting Cytochrome P450 3A4-Ligand Interactions Using Ritonavir Analogues.
Biochemistry, 52, 2013
4K9W
DownloadVisualize
BU of 4k9w by Molmil
Complex of human CYP3A4 with a desoxyritonavir analog
分子名称: Cytochrome P450 3A4, N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-[(2R,5S)-1-phenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}octan-2-yl]-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F, Poulos, T.L.
登録日2013-04-21
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Dissecting Cytochrome P450 3A4-Ligand Interactions Using Ritonavir Analogues.
Biochemistry, 52, 2013
4K9T
DownloadVisualize
BU of 4k9t by Molmil
Complex of CYP3A4 with a desoxyritonavir analog
分子名称: Cytochrome P450 3A4, N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-(4-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}butyl)-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F, Poulos, T.L.
登録日2013-04-21
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dissecting Cytochrome P450 3A4-Ligand Interactions Using Ritonavir Analogues.
Biochemistry, 52, 2013
6OOB
DownloadVisualize
BU of 6oob by Molmil
Human CYP3A4 bound to a suicide substrate
分子名称: 4-{[(2Z,6S)-6,7-dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}-7H-furo[3,2-g][1]benzopyran-7-one, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.F.
登録日2019-04-22
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin.
Int J Mol Sci, 20, 2019
6OOA
DownloadVisualize
BU of 6ooa by Molmil
Human CYP3A4 bound to a drug substrate
分子名称: (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-ethyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl [(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]acetate, Cytochrome P450 3A4, GLYCEROL, ...
著者Sevrioukova, I.F.
登録日2019-04-22
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin.
Int J Mol Sci, 20, 2019
6OO9
DownloadVisualize
BU of 6oo9 by Molmil
Human CYP3A4 bound to a drug mibefradil
分子名称: (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate, 1,2-ETHANEDIOL, Cytochrome P450 3A4, ...
著者Sevrioukova, I.F.
登録日2019-04-22
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin.
Int J Mol Sci, 20, 2019
1OQR
DownloadVisualize
BU of 1oqr by Molmil
Crystal structure of C73S mutant of putidaredoxin, a [2Fe-2S] ferredoxin from Pseudomonas putida, at 1.65A resolution
分子名称: FE2/S2 (INORGANIC) CLUSTER, Putidaredoxin
著者Sevrioukova, I.F, Garcia, C, Li, H, Bhaskar, B, Poulos, T.L.
登録日2003-03-10
公開日2003-11-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of putidaredoxin, the [2Fe-2S] component of the P450cam monooxygenase system from Pseudomonas putida
J.MOL.BIOL., 333, 2003
1OQQ
DownloadVisualize
BU of 1oqq by Molmil
Crystal structure of C73S/C85S mutant of putidaredoxin, a [2Fe-2S] ferredoxin from Pseudomonas putida, at 1.47A resolution
分子名称: FE2/S2 (INORGANIC) CLUSTER, Putidaredoxin
著者Sevrioukova, I.F, Garcia, C, Li, H, Bhaskar, B, Poulos, T.L.
登録日2003-03-10
公開日2003-11-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystal structure of putidaredoxin, the [2Fe-2S] component of the P450cam monooxygenase system from Pseudomonas putida
J.MOL.BIOL., 333, 2003
1Q1R
DownloadVisualize
BU of 1q1r by Molmil
Crystal Structure of Putidaredoxin Reductase from Pseudomonas putida
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putidaredoxin reductase
著者Sevrioukova, I.F, Li, H, Poulos, T.L.
登録日2003-07-22
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase.
J.Mol.Biol., 336, 2004
1Q1W
DownloadVisualize
BU of 1q1w by Molmil
Crystal Structure of Putidaredoxin Reductase from Pseudomonas putida
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putidaredoxin reductase
著者Sevrioukova, I.F, Li, H, Poulos, T.L.
登録日2003-07-22
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase.
J.Mol.Biol., 336, 2004
1XLQ
DownloadVisualize
BU of 1xlq by Molmil
Crystal structure of reduced C73S putidaredoxin from Pseudomonas putida
分子名称: FE2/S2 (INORGANIC) CLUSTER, Putidaredoxin
著者Sevrioukova, I.F.
登録日2004-09-30
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Redox-dependent Structural Reorganization in Putidaredoxin, a Vertebrate-type [2Fe-2S] Ferredoxin from Pseudomonas putida.
J.Mol.Biol., 347, 2005
1XLN
DownloadVisualize
BU of 1xln by Molmil
Crystal structure of oxidized C73S/C85S putidaredoxin, a [2Fe-2S] ferredoxin from Pseudomonas putida
分子名称: FE2/S2 (INORGANIC) CLUSTER, Putidaredoxin
著者Sevrioukova, I.F.
登録日2004-09-30
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Redox-dependent Structural Reorganization in Putidaredoxin, a Vertebrate-type [2Fe-2S] Ferredoxin from Pseudomonas putida.
J.Mol.Biol., 347, 2005

219140

件を2024-05-01に公開中

PDB statisticsPDBj update infoContact PDBjnumon