8SO2
Human CYP3A4 bound to a substrate
Summary for 8SO2
| Entry DOI | 10.2210/pdb8so2/pdb |
| Descriptor | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, CAFFEINE, ... (4 entities in total) |
| Functional Keywords | substrate, complex, oxidoreductase, oxidoreductase-substrate complex, oxidoreductase/substrate |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 57539.44 |
| Authors | Sevrioukova, I.F. (deposition date: 2023-04-28, release date: 2023-08-02, Last modification date: 2023-09-06) |
| Primary citation | Sevrioukova, I.F. Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding. J.Biol.Chem., 299:105117-105117, 2023 Cited by PubMed: 37524132DOI: 10.1016/j.jbc.2023.105117 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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