6OOB
Human CYP3A4 bound to a suicide substrate
Summary for 6OOB
Entry DOI | 10.2210/pdb6oob/pdb |
Descriptor | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, 4-{[(2Z,6S)-6,7-dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}-7H-furo[3,2-g][1]benzopyran-7-one, ... (4 entities in total) |
Functional Keywords | substrate, complex, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 56746.71 |
Authors | Sevrioukova, I.F. (deposition date: 2019-04-22, release date: 2019-09-11, Last modification date: 2023-10-11) |
Primary citation | Sevrioukova, I.F. Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin. Int J Mol Sci, 20:-, 2019 Cited by PubMed: 31480231DOI: 10.3390/ijms20174245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.202 Å) |
Structure validation
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