7MK8
Crystal structure of a surface mutant of human fetal-specific CYP3A7 bound to dithiothreitol
Summary for 7MK8
Entry DOI | 10.2210/pdb7mk8/pdb |
Descriptor | Isoform 2 of Cytochrome P450 3A7, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total) |
Functional Keywords | cytochrome p450, cyp3a7, surface mutations, dithiothreitol, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 121058.27 |
Authors | Sevrioukova, I.F. (deposition date: 2021-04-21, release date: 2021-06-02, Last modification date: 2023-10-18) |
Primary citation | Sevrioukova, I.F. Structural Basis for the Diminished Ligand Binding and Catalytic Ability of Human Fetal-Specific CYP3A7. Int J Mol Sci, 22:-, 2021 Cited by PubMed: 34072457DOI: 10.3390/ijms22115831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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