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4BXX
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BU of 4bxx by Molmil
Arrested RNA polymerase II-Bye1 complex
分子名称: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ...
著者Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
登録日2013-07-16
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue
Proc.Natl.Acad.Sci.USA, 110, 2013
4BXZ
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BU of 4bxz by Molmil
RNA Polymerase II-Bye1 complex
分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
著者Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
登録日2013-07-16
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.8 Å)
主引用文献Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue
Proc.Natl.Acad.Sci.USA, 110, 2013
4BY1
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elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP
分子名称: 5'-D(*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP *TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*AP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ...
著者Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
登録日2013-07-17
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue
Proc.Natl.Acad.Sci.USA, 110, 2013
4BY7
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elongating RNA Polymerase II-Bye1 TLD complex
分子名称: , 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3', 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
登録日2013-07-18
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
6J9J
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BU of 6j9j by Molmil
crystal structure of SESTD2 in complex with H3.3S31phK36M peptide
分子名称: H3.3S31phK36M(29-42), Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Yang, S, Li, H.T.
登録日2019-01-23
公開日2020-02-26
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Histone H3.3 phosphorylation amplifies stimulation-induced transcription.
Nature, 583, 2020
4X34
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Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2
分子名称: THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS, Tumor suppressor p53-binding protein 1
著者Tong, Q, Kutateladze, T.G.
登録日2014-11-27
公開日2015-03-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
5JGC
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BU of 5jgc by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A, L130A, L179A and I195A mutant
分子名称: Protein TPR1, ZINC ION
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-20
公開日2017-07-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
6MON
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BU of 6mon by Molmil
Crystal structure of human SMYD2 in complex with Nle-peptide inhibitor
分子名称: GLYCEROL, LYS-LEU-NLE-SER-LYS-ARG-GLY, N-lysine methyltransferase SMYD2, ...
著者Spellmon, N, Cornett, E, Brunzelle, J, Rothbart, S, Yang, Z.
登録日2018-10-04
公開日2018-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.711 Å)
主引用文献A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity.
Sci Adv, 4, 2018
6F57
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BU of 6f57 by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA
分子名称: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ...
著者Zhang, Z.M, Song, J.
登録日2017-12-01
公開日2018-01-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.098 Å)
主引用文献Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
7LHY
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BU of 7lhy by Molmil
Caenorhabditis elegans SWSN-4 (SMARCA4-BRG1) ATPase Bromodomain in complex with a modified histone H3, N6-epsilon-acetyl-L-lysine 14 (H3K14ac) polypeptide
分子名称: H3(7-20)K14ac, SWI/SNF nucleosome remodeling complex component
著者Enriquez, P, Rose, R.B.
登録日2021-01-26
公開日2021-09-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14.
J.Biol.Chem., 297, 2021
5C6D
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BU of 5c6d by Molmil
Crystal structure of USP7 in complex with UHRF1
分子名称: E3 ubiquitin-protein ligase UHRF1, Ubiquitin carboxyl-terminal hydrolase 7
著者Zhang, Z.-M, Song, J.
登録日2015-06-22
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
Cell Rep, 12, 2015
4RG2
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BU of 4rg2 by Molmil
Tudor Domain of Tumor suppressor p53BP1 with small molecule ligand
分子名称: 1,2-ETHANEDIOL, 3-bromo-N-[3-(tert-butylamino)propyl]benzamide, Tumor suppressor p53-binding protein 1, ...
著者Dong, A, Mader, P, James, L, Perfetti, M, Tempel, W, Frye, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC)
登録日2014-09-29
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.
ACS Chem. Biol., 10, 2015
5YX2
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BU of 5yx2 by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites
分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
著者Zhang, Z.M, Song, J.
登録日2017-12-01
公開日2018-01-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.653 Å)
主引用文献Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
4L7X
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BU of 4l7x by Molmil
Crystal structure of the DIDO PHD finger in complex with H3K4me3
分子名称: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION
著者Tong, Q, Gatchalian, J, Kutateladze, T.G.
登録日2013-06-14
公開日2013-07-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Dido3 PHD Modulates Cell Differentiation and Division.
Cell Rep, 4, 2013
4L58
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BU of 4l58 by Molmil
Crystal structure of the MLL5 PHD finger in complex with H3K4me3
分子名称: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION
著者Tong, Q, Ali, M, Kutateladze, T.G.
登録日2013-06-10
公開日2013-06-26
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Molecular basis for chromatin binding and regulation of MLL5.
Proc.Natl.Acad.Sci.USA, 110, 2013
6O7G
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BU of 6o7g by Molmil
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
分子名称: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
著者Zhang, Y, Kutateladze, T.G.
登録日2019-03-07
公開日2019-05-22
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
6BRR
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BU of 6brr by Molmil
Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites
分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
著者Zhang, Z.M, Song, J.
登録日2017-11-30
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
2M0O
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BU of 2m0o by Molmil
The solution structure of human PHF1 in complex with H3K36me3
分子名称: H3K36me3 peptide, PHD finger protein 1
著者Song, J, Patel, D.J.
登録日2012-10-30
公開日2013-01-16
最終更新日2013-02-27
実験手法SOLUTION NMR
主引用文献An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting.
Mol.Cell, 49, 2013
2MWO
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BU of 2mwo by Molmil
Solution structure of 53BP1 tandem Tudor domains in complex with a p53K370me2 peptide
分子名称: Cellular tumor antigen p53, Tumor suppressor p53-binding protein 1
著者Cui, G, Botuyan, M.V, Mer, G.
登録日2014-11-15
公開日2014-12-10
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23, 2015
2MWP
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BU of 2mwp by Molmil
Solution structure of 53BP1 tandem Tudor domains in complex with a p53K382me2 peptide
分子名称: Cellular tumor antigen p53, Tumor suppressor p53-binding protein 1
著者Cui, G, Botuyan, M.V, Mer, G.
登録日2014-11-15
公開日2014-12-10
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23, 2015
5JA5
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BU of 5ja5 by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A and L130A mutant in complex with rice D53 repressor EAR peptide motif
分子名称: Protein TPR1, The rice D53 peptide (a.a. 794-808), ZINC ION
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-12
公開日2017-07-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JHP
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BU of 5jhp by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L179A and I195A mutant in complex with rice D53 repressor EAR peptide motif
分子名称: Protein TPR1, The rice D53 EAR peptide (794-808)
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-21
公開日2017-07-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5J9K
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BU of 5j9k by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) in complex with rice D53 repressor EAR peptide motif
分子名称: Protein TPR1, ZINC ION, rice D53 peptide 794-808
著者Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
登録日2016-04-10
公開日2017-07-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5SVX
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BU of 5svx by Molmil
MORC3 CW in complex with histone H3K4me3
分子名称: H3K4me3, MORC family CW-type zinc finger protein 3, ZINC ION
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-08
公開日2016-10-05
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016
5SVY
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BU of 5svy by Molmil
MORC3 CW in complex with histone H3K4me1
分子名称: ACETATE ION, H3K4me1, MORC family CW-type zinc finger protein 3, ...
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-08
公開日2016-10-05
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016

 

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