6J9J

crystal structure of SESTD2 in complex with H3.3S31phK36M peptide

Summary for 6J9J

• Entry DOI: 10.2210/pdb6j9j/pdb
• Descriptor: Histone-lysine N-methyltransferase SETD2, H3.3S31phK36M(29-42), ZINC ION, ... (6 entities in total)
• Functional Keywords: methyltransferase, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 32149.59

Authors

Yang, S.,Li, H.T. (deposition date: 2019-01-23, release date: 2020-02-26, Last modification date: 2020-08-12)

• Primary citation: Armache, A.,Yang, S.,Martinez de Paz, A.,Robbins, L.E.,Durmaz, C.,Cheong, J.Q.,Ravishankar, A.,Daman, A.W.,Ahimovic, D.J.,Klevorn, T.,Yue, Y.,Arslan, T.,Lin, S.,Panchenko, T.,Hrit, J.,Wang, M.,Thudium, S.,Garcia, B.A.,Korb, E.,Armache, K.J.,Rothbart, S.B.,Hake, S.B.,Allis, C.D.,Li, H.,Josefowicz, S.Z.; Histone H3.3 phosphorylation amplifies stimulation-induced transcription.; Nature, 583:852-857, 2020; PubMed: 32699416; DOI: 10.1038/s41586-020-2533-0

Experimental method

X-RAY DIFFRACTION (1.78 Å)