5JHP
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L179A and I195A mutant in complex with rice D53 repressor EAR peptide motif
Summary for 5JHP
Entry DOI | 10.2210/pdb5jhp/pdb |
Related | 5J9K 5JA5 5JGC |
Descriptor | Protein TPR1, The rice D53 EAR peptide (794-808) (2 entities in total) |
Functional Keywords | transcription repression, transcriptional corepressor topless, alpha-helical structure, tetramer, transcriptional repressor d53, transcription |
Biological source | Oryza sativa (Rice) More |
Total number of polymer chains | 5 |
Total formula weight | 101142.76 |
Authors | Ke, J.,Ma, H.,Gu, X.,Brunzelle, J.S.,Xu, H.E.,Melcher, K. (deposition date: 2016-04-21, release date: 2017-07-05, Last modification date: 2023-09-27) |
Primary citation | Ma, H.,Duan, J.,Ke, J.,He, Y.,Gu, X.,Xu, T.H.,Yu, H.,Wang, Y.,Brunzelle, J.S.,Jiang, Y.,Rothbart, S.B.,Xu, H.E.,Li, J.,Melcher, K. A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex. Sci Adv, 3:e1601217-e1601217, 2017 Cited by PubMed: 28630893DOI: 10.1126/sciadv.1601217 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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