5JGC

Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A, L130A, L179A and I195A mutant

Summary for 5JGC

Entry DOI	10.2210/pdb5jgc/pdb
Related	5J9K 5JA5 5JHP
Descriptor	Protein TPR1, ZINC ION (3 entities in total)
Functional Keywords	transcription repression, transcriptional corepressor topless, alpha-helical structure, tetramer, transcriptional repressor d53, transcription
Biological source	Oryza sativa (Rice)
Total number of polymer chains	1
Total formula weight	24800.70
Authors	Ke, J.,Ma, H.,Gu, X.,Brunzelle, J.S.,Xu, H.E.,Melcher, K. (deposition date: 2016-04-20, release date: 2017-07-05, Last modification date: 2024-03-06)
Primary citation	Ma, H.,Duan, J.,Ke, J.,He, Y.,Gu, X.,Xu, T.H.,Yu, H.,Wang, Y.,Brunzelle, J.S.,Jiang, Y.,Rothbart, S.B.,Xu, H.E.,Li, J.,Melcher, K. A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex. Sci Adv, 3:e1601217-e1601217, 2017 Cited by PubMed: 28630893 DOI: 10.1126/sciadv.1601217 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.08 Å)

Structure validation