4X34

Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2

Summary for 4X34

Entry DOI	10.2210/pdb4x34/pdb
Descriptor	Tumor suppressor p53-binding protein 1, THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS (3 entities in total)
Functional Keywords	posttranslational modifications, tandem tudor domain of 53bp1, transcription-transcription inhibitor complex, transcription/transcription inhibitor
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	29934.13
Authors	Tong, Q.,Kutateladze, T.G. (deposition date: 2014-11-27, release date: 2015-03-04, Last modification date: 2023-11-15)
Primary citation	Tong, Q.,Mazur, S.J.,Rincon-Arano, H.,Rothbart, S.B.,Kuznetsov, D.M.,Cui, G.,Liu, W.H.,Gete, Y.,Klein, B.J.,Jenkins, L.,Mer, G.,Kutateladze, A.G.,Strahl, B.D.,Groudine, M.,Appella, E.,Kutateladze, T.G. An Acetyl-Methyl Switch Drives a Conformational Change in p53. Structure, 23:322-331, 2015 Cited by PubMed: 25651062 DOI: 10.1016/j.str.2014.12.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.801 Å)

Structure validation