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7Q4M
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Type II beta-amyloid 42 Filaments from Human Brain
分子名称: Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
著者Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
登録日2021-11-01
公開日2021-11-24
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Science, 375, 2022
7Q4B
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Type I beta-amyloid 42 Filaments from Human Brain
分子名称: Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
著者Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
登録日2021-10-30
公開日2021-11-24
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Science, 375, 2022
8BG9
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Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta
分子名称: Amyloid-beta protein 40
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BG0
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Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40
分子名称: Amyloid-beta precursor protein
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BFZ
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Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42
分子名称: Amyloid-beta precursor protein
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordberg, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
4LD9
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Crystal structure of the N-terminally acetylated BAH domain of Sir3 bound to the nucleosome core particle
分子名称: Histone H2A, Histone H2B 1.1, Histone H3.2, ...
著者Arnaudo, N, Fernandez, I.S, McLaughlin, S.H, Peak-Chew, S.Y, Rhodes, D, Martino, F.
登録日2013-06-24
公開日2013-08-14
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (3.306 Å)
主引用文献The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle.
Nat.Struct.Mol.Biol., 20, 2013
8OX0
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Structure of apo telomeric nucleosome
分子名称: Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ...
著者Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D.
登録日2023-04-28
公開日2023-08-30
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
8OX1
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Structure of TRF1core in complex with telomeric nucleosome
分子名称: Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ...
著者Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D.
登録日2023-04-28
公開日2023-08-30
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
8QN7
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Amyloid-beta 40 type 1 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy
分子名称: Amyloid-beta A4 protein
著者Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2023-09-25
公開日2023-12-13
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023
8QN6
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Amyloid-beta 40 type 2 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy
分子名称: Amyloid-beta A4 protein
著者Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2023-09-25
公開日2023-12-13
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023
8ONS
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TAF15 amyloid fold in atypical FTLD - Individual 1
分子名称: TATA-binding protein-associated factor 2N
著者Tetter, S, Ryskeldi-Falcon, B.
登録日2023-04-03
公開日2023-12-06
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (1.97 Å)
主引用文献TAF15 amyloid filaments in frontotemporal lobar degeneration.
Nature, 625, 2024
1HG4
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Ultraspiracle ligand binding domain from Drosophila melanogaster
分子名称: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ULTRASPIRACLE
著者Schwabe, J.W.R, Clayton, G.M.
登録日2000-12-12
公開日2001-02-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of the Ultraspiracle Ligand-Binding Domain Reveals a Nuclear Receptor Locked in an Inactive Conformation
Proc.Natl.Acad.Sci.USA, 98, 2001
8QQF
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TBC1D23 PH domain complexed with STX16 TLY motif
分子名称: GLYCEROL, PHOSPHATE ION, Syntaxin-16, ...
著者Kaufman, J.G, Owen, D.J.
登録日2023-10-04
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Cargo selective vesicle tethering: The structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23.
Sci Adv, 10, 2024
8BQW
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Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy
分子名称: Alpha-synuclein, Unknown protein
著者Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
登録日2023-01-18
公開日2023-02-22
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
8BQV
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Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy
分子名称: Alpha-synuclein, Unknown protein
著者Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
登録日2023-01-18
公開日2023-02-22
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
8CE7
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Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
分子名称: Alpha-synuclein
著者Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
登録日2023-02-01
公開日2023-03-01
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
8BPO
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Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S.
登録日2022-11-17
公開日2023-07-05
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
Mol.Cell, 83, 2023
8CG3
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Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)
分子名称: TAR DNA-binding protein 43
著者Arseni, D, Ryskeldi-Falcon, B.
登録日2023-02-03
公開日2023-08-02
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8CGG
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Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2)
分子名称: TAR DNA-binding protein 43
著者Arseni, D, Ryskeldi-Falcon, B.
登録日2023-02-04
公開日2023-08-02
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8CGH
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Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3)
分子名称: TAR DNA-binding protein 43
著者Arseni, D, Ryskeldi-Falcon, B.
登録日2023-02-04
公開日2023-08-02
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8CIO
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Cryo-EM structure of the CupE pilus from Pseudomonas aeruginosa
分子名称: SCPU domain-containing protein
著者Boehning, J, Bharat, T.A.M.
登録日2023-02-10
公開日2023-03-22
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Architecture of the biofilm-associated archaic Chaperone-Usher pilus CupE from Pseudomonas aeruginosa.
Plos Pathog., 19, 2023

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