7V5C
 
 | | Cryo-EM structure of the mouse ABCB9 (ADP.BeF3-bound) | | Descriptor: | ABC-type oligopeptide transporter ABCB9, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | | Deposit date: | 2021-08-17 | | Release date: | 2022-10-19 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase.
Nat Commun, 13, 2022
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7V5D
 | | Cryo-EM structure of the mouse ABCB9 (PG-bound) | | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ABC-type oligopeptide transporter ABCB9 | | Authors: | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Ju, S, Kim, J.W, Min, D.S, Jin, M.S. | | Deposit date: | 2021-08-17 | | Release date: | 2022-10-19 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase.
Nat Commun, 13, 2022
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7VFI
 | | Cryo-EM structure of the mouse TAPL (9mer-peptide bound) | | Descriptor: | ABC-type oligopeptide transporter ABCB9, ARG-ARG-TYR-GLN-LYS-SER-THR-GLU-LEU, CHOLESTEROL HEMISUCCINATE | | Authors: | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | | Deposit date: | 2021-09-13 | | Release date: | 2022-10-19 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase.
Nat Commun, 13, 2022
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9LSK
 | | Cryo-EM structure of the Klebsiella pneumoniae CitS (citrate-bound occluded state) | | Descriptor: | CITRIC ACID, Citrate/sodium symporter, PALMITIC ACID | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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9LSJ
 | | Cryo-EM structure of the G15C-R66C and T83C-T83C diabody complex (CitS-diabody #7-TLR3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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9LSI
 | | Cryo-EM structure of the S82C-S82C diabody complex (CitS-diabody #2-TLR3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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9LSH
 | | Cryo-EM structure of the wild-type diabody complex (CitS-diabody #1-TLR3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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8K7C
 | | Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION, ... | | Authors: | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | | Deposit date: | 2023-07-26 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
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8K7B
 | | post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound) | | Descriptor: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ATP-binding cassette sub-family B member 6, ... | | Authors: | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | | Deposit date: | 2023-07-26 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
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7DNZ
 | | Cryo-EM structure of the human ABCB6 (Hemin and GSH-bound) | | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Kim, S, Lee, S.S, Park, J.G, Kim, J.W, Kim, S, Kim, N.J, Hong, S, Kang, J.Y, Jin, M.S. | | Deposit date: | 2020-12-11 | | Release date: | 2022-06-22 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6.
Mol.Cells, 45, 2022
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7DNY
 | | Cryo-EM structure of the human ABCB6 (coproporphyrin III-bound) | | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Kim, S, Lee, S.S, Park, J.G, Kim, J.W, Kim, S, Kim, N.J, Hong, S, Kang, J.Y, Jin, M.S. | | Deposit date: | 2020-12-11 | | Release date: | 2022-06-22 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6.
Mol.Cells, 45, 2022
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8ZKW
 | | Cryo-EM structure of the Drosophila INDY (apo-asymmetric, pH 6) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Protein I'm not dead yet | | Authors: | Kim, S, Park, J.G, Choi, S.H, Kim, J.W, Jin, M.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Cryo-EM structures reveal the cation-independent citrate transport mechanism of the Drosophila longevity protein, INDY
To Be Published
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8ZL2
 | | Cryo-EM structure of the Drosophila INDY (DIDS-bound asymmetric, pH 6) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Kim, S, Park, J.G, Choi, S.H, Kim, J.W, Jin, M.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo-EM structures reveal the cation-independent citrate transport mechanism of the Drosophila longevity protein, INDY
To Be Published
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8ZL1
 | | Cryo-EM structure of the Drosophila INDY (apo outward-open, pH 6) | | Descriptor: | PHOSPHATIDYLETHANOLAMINE, Protein I'm not dead yet | | Authors: | Kim, S, Park, J.G, Choi, S.H, Kim, J.W, Jin, M.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Cryo-EM structures reveal the cation-independent citrate transport mechanism of the Drosophila longevity protein, INDY
To Be Published
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8ZKZ
 | | Cryo-EM structure of the Drosophila INDY (apo-asymmetric, pH8) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Protein I'm not dead yet | | Authors: | Kim, S, Park, J.G, Choi, S.H, Kim, J.W, Jin, M.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM structures reveal the cation-independent citrate transport mechanism of the Drosophila longevity protein, INDY
To Be Published
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8ZL3
 | | Cryo-EM structure of the Drosophila INDY (DIDS-bound outward-open, pH 6) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Kim, S, Park, J.G, Choi, S.H, Kim, J.W, Jin, M.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM structures reveal the cation-independent citrate transport mechanism of the Drosophila longevity protein, INDY
To Be Published
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8ZL6
 | | Cryo-EM structure of the Drosophila INDY (apo inward-open, pH 8) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Protein I'm not dead yet | | Authors: | Kim, S, Park, J.G, Choi, S.H, Kim, J.W, Jin, M.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo-EM structures reveal the cation-independent citrate transport mechanism of the Drosophila longevity protein, INDY
To Be Published
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8ZL4
 | | Cryo-EM structure of the Drosophila INDY (citrate-bound inward-occluded, pH 6) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Kim, S, Park, J.G, Choi, S.H, Kim, J.W, Jin, M.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Cryo-EM structures reveal the cation-independent citrate transport mechanism of the Drosophila longevity protein, INDY
To Be Published
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8GUW
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3NJ4
 | | Fluoro-neplanocin A in Human S-Adenosylhomocysteine Hydrolase | | Descriptor: | (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Jeong, L.S, Lee, K.M, Hwang, K.Y, Choi, S, Heo, Y.S. | | Deposit date: | 2010-06-17 | | Release date: | 2011-05-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
J.Med.Chem., 54, 2011
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6WKS
 | | Structure of SARS-CoV-2 nsp16/nsp10 in complex with RNA cap analogue (m7GpppA) and S-adenosylmethionine | | Descriptor: | 1,2-ETHANEDIOL, 2'-O-methyltransferase, ADENOSINE, ... | | Authors: | Gupta, Y.K, Viswanathan, T, Arya, S, Qi, S, Misra, A, Chan, S.-H. | | Deposit date: | 2020-04-16 | | Release date: | 2020-05-06 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis of RNA cap modification by SARS-CoV-2.
Nat Commun, 11, 2020
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3FDR
 | | Crystal structure of TDRD2 | | Descriptor: | Tudor and KH domain-containing protein | | Authors: | Amaya, M.F, Adams, M.A, Guo, Y, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-11-26 | | Release date: | 2009-01-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi
Proc.Natl.Acad.Sci.USA, 106, 2009
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