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5L1C
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BU of 5l1c by Molmil
Heteronuclear Solution Structure of Chlorotoxin
Descriptor: Chlorotoxin
Authors:Mobli, M, Braga, C.B, Sharma, G.
Deposit date:2016-07-28
Release date:2017-08-09
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Solution structure and dynamics of Chlorotoxin, a glioma specific scorpion toxin
To Be Published
2MUB
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BU of 2mub by Molmil
Solution structure of the analgesic sea anemone peptide APETx2
Descriptor: Toxin APETx2
Authors:Mobli, M, King, G.F, Rosengren, K.J, Jensen, J.E.
Deposit date:2014-09-07
Release date:2014-12-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores.
J.Med.Chem., 57, 2014
2KSL
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BU of 2ksl by Molmil
Structure of the insecticidal toxin TaITX-1
Descriptor: U1-agatoxin-Ta1a
Authors:Mobli, M, King, G.F.
Deposit date:2010-01-07
Release date:2011-01-19
Last modified:2015-06-24
Method:SOLUTION NMR
Cite:Weaponization of a Hormone: Convergent Recruitment of Hyperglycemic Hormone into the Venom of Arthropod Predators
Structure, 2015
2LY7
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BU of 2ly7 by Molmil
B-flap domain of RNA polymerase (B. subtilis)
Descriptor: DNA-directed RNA polymerase subunit beta
Authors:Mobli, M.
Deposit date:2012-09-12
Release date:2014-03-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.
Nucleic Acids Res., 43, 2015
2MF3
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BU of 2mf3 by Molmil
SGTX-Sf1a
Descriptor: U2-segestritoxin-Sf1a
Authors:Mobli, M, Bende, N.S, King, G.F.
Deposit date:2013-10-04
Release date:2014-10-15
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large beta-hairpin loop.
Febs J., 282, 2015
2MT4
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BU of 2mt4 by Molmil
Solution structure of the N-terminal domain of NUSA from B. Subtilis
Descriptor: Transcription termination/antitermination protein NusA
Authors:Mobli, M, Lewis, P.J.
Deposit date:2014-08-12
Release date:2015-02-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.
Nucleic Acids Res., 43, 2015
7RZ3
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BU of 7rz3 by Molmil
The solution structure of remipede double-ICK toxin phi-Xibalbin3-Xt3a
Descriptor: Xt3a
Authors:Maxwell, M, Chin, Y.K, Mobli, M.
Deposit date:2021-08-27
Release date:2022-08-31
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:A bivalent remipede toxin promotes calcium release via ryanodine receptor activation.
Nat Commun, 14, 2023
7RM8
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BU of 7rm8 by Molmil
Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide
Descriptor: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion
Authors:Healy, M.D, Collins, B.M, Mobli, M.
Deposit date:2021-07-26
Release date:2022-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Structure, 30, 2022
6URP
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BU of 6urp by Molmil
RDC refined solution structure of the insecticidal toxin Ta1a
Descriptor: U1-agatoxin-Ta1a
Authors:Ramanujam, V, Shen, Y, Ying, J, Mobli, M.
Deposit date:2019-10-24
Release date:2020-01-22
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Residual Dipolar Couplings for Resolving Cysteine Bridges in Disulfide-Rich Peptides.
Front Chem, 7, 2019
8JZM
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BU of 8jzm by Molmil
The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210
Descriptor: Toll/interleukin-1 receptor domain-containing adapter protein
Authors:Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B.
Deposit date:2023-07-05
Release date:2024-05-01
Method:SOLUTION NMR
Cite:o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
J Enzyme Inhib Med Chem, 39, 2024
8EPY
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BU of 8epy by Molmil
The solution structure of abxF in complex with its product (-)-ABX, an enzyme catalyzing the formation of the chiral spiroketal of an anthrabenzoxocinone antibiotic, (-)-ABX
Descriptor: (6R,16R)-3,11,13,15-tetrahydroxy-1,6,9,9-tetramethyl-6,7,9,16-tetrahydro-14H-6,16-epoxyanthra[2,3-e]benzo[b]oxocin-14-one, Glyoxalase
Authors:Jia, X, Yan, X, Qu, X, Mobli, M.
Deposit date:2022-10-06
Release date:2024-04-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The solution structure of abxF, an enzyme catalyzing the formation of chiral spiroketal of an antibiotics, (-)-ABX.
To Be Published
8EO9
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BU of 8eo9 by Molmil
The solution structure of abxF, an enzyme catalyzing the formation of chiral spiroketal of an antibiotics, (-)-ABX
Descriptor: Glyoxalase
Authors:Jia, X, Yan, X, Mobli, M, Qu, X.
Deposit date:2022-10-02
Release date:2024-04-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The solution structure of abxF, an enzyme catalyzing the formation of chiral spiroketal of an antibiotics, (-)-ABX.
To Be Published
8FD4
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BU of 8fd4 by Molmil
Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao
Descriptor: Jingzhaotoxin F7-10.36
Authors:Sharma, G, Jia, X, Chin, Y.K.Y, Mobli, M.
Deposit date:2022-12-01
Release date:2023-11-08
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao
To Be Published
5I2P
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BU of 5i2p by Molmil
Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a (W6A in native sequence numbering)
Descriptor: W7A mu-TRTX-Pre1a Toxin
Authors:Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D.
Deposit date:2016-02-09
Release date:2017-06-28
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a
To Be Published
5I1X
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BU of 5i1x by Molmil
Resonance assignments and NMR structure determination of tarantula toxin, F8A mutant of beta-TRTX-Pre1a
Descriptor: mu-TRTX-Pre1a toxin
Authors:Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D.
Deposit date:2016-02-07
Release date:2017-02-08
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Resonance assignments and NMR structure determination of tarantula toxin, mu-TRTX-Pre1a
To Be Published
8FA3
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BU of 8fa3 by Molmil
Structure of N-terminal of Schistosoma japonicum asparaginyl-tRNA synthetase
Descriptor: Asparagine--tRNA ligase
Authors:Peck, Y, Daly, N.L, Mobli, M.
Deposit date:2022-11-25
Release date:2023-09-06
Last modified:2024-09-25
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal extension domain of a Schistosoma japonicum asparaginyl-tRNA synthetase.
J.Biomol.Struct.Dyn., 42, 2024
7LIE
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BU of 7lie by Molmil
The isolated chicken ASIC1a thumb domain (ATD-c1a) retains the structure and ligand binding properties of the full length chicken ASIC1a
Descriptor: Acid-sensing ion channel 1
Authors:Mishra, B.M, Mobli, M.
Deposit date:2021-01-27
Release date:2022-08-10
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:A reductionist approach for studying the ASIC thumb domain to screen for channel modulators as novel therapeutic leads
To Be Published
6CUC
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BU of 6cuc by Molmil
Solution structure of double knot toxin (DkTx)
Descriptor: Tau-theraphotoxin-Hs1a
Authors:Ramanujam, V, Mobli, M.
Deposit date:2018-03-25
Release date:2019-03-27
Last modified:2024-04-24
Method:SOLUTION NMR
Cite:Structural Basis of the Bivalency of the TRPV1 Agonist DkTx.
Angew.Chem.Int.Ed.Engl., 63, 2024
5V0Y
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BU of 5v0y by Molmil
Solution structure of arenicin-3.
Descriptor: arenicin-3
Authors:Edwards, I.A, Mobli, M.
Deposit date:2017-02-28
Release date:2018-08-08
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria
Nat Commun, 2020
5WOE
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BU of 5woe by Molmil
Solution structure of the sorting nexin 25 phox-homology domain
Descriptor: Sorting nexin-25
Authors:Chin, Y.K.Y, Mas, C, Mobli, M, Collins, B.M.
Deposit date:2017-08-01
Release date:2018-08-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
5T3M
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BU of 5t3m by Molmil
Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7
Descriptor: Mu-theraphotoxin-Hs2a
Authors:Rahnama, S, Sharma, G, Mobli, M.
Deposit date:2016-08-25
Release date:2017-09-06
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.
PLoS ONE, 12, 2017
5V11
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BU of 5v11 by Molmil
Solution structure of arenicin-3 synthetic analog.
Descriptor: AA139
Authors:Edwards, I.A, Mobli, M.
Deposit date:2017-03-01
Release date:2018-08-08
Last modified:2020-01-08
Method:SOLUTION NMR
Cite:Elucidating the Lipid Binding Properties of Membrane-Active Peptides Using Cyclised Nanodiscs.
Front Chem, 7, 2019
5UZB
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BU of 5uzb by Molmil
Cryo-EM structure of the MAL TIR domain filament
Descriptor: Toll/interleukin-1 receptor domain-containing adapter protein
Authors:Ve, T, Vajjhala, P.R, Hedger, A, Croll, T, DiMaio, F, Horsefield, S, Yu, X, Lavrencic, P, Hassan, Z, Morgan, G.P, Mansell, A, Mobli, M, O'Carrol, A, Chauvin, B, Gambin, Y, Sierecki, E, Landsberg, M.J, Stacey, K.J, Egelman, E.H, Kobe, B.
Deposit date:2017-02-25
Release date:2017-07-26
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.
Nat. Struct. Mol. Biol., 24, 2017
5U87
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BU of 5u87 by Molmil
NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin
Descriptor: Preproalbumin PawS1
Authors:Franke, B, James, A.M, Mobli, M, Colgrave, M.L, Mylne, J.S, Rosengren, K.J.
Deposit date:2016-12-14
Release date:2017-03-01
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin
to be published
2MPQ
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BU of 2mpq by Molmil
Solution structure of the sodium channel toxin Hd1a
Descriptor: Hd1a
Authors:Klint, J.K, Mobli, M, King, G.F.
Deposit date:2014-06-01
Release date:2015-03-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.
Br.J.Pharmacol., 172, 2015

 

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