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8EPY

The solution structure of abxF in complex with its product (-)-ABX, an enzyme catalyzing the formation of the chiral spiroketal of an anthrabenzoxocinone antibiotic, (-)-ABX

Summary for 8EPY
Entry DOI10.2210/pdb8epy/pdb
DescriptorGlyoxalase, (6R,16R)-3,11,13,15-tetrahydroxy-1,6,9,9-tetramethyl-6,7,9,16-tetrahydro-14H-6,16-epoxyanthra[2,3-e]benzo[b]oxocin-14-one (2 entities in total)
Functional Keywordscyana 3.98.13, enzyme, catalysis, chiral spiroketal, biosynthetic protein-antibiotic complex, biosynthetic protein/antibiotic
Biological sourceStreptomyces sp.
Total number of polymer chains1
Total formula weight25652.45
Authors
Jia, X.,Yan, X.,Qu, X.,Mobli, M. (deposition date: 2022-10-06, release date: 2024-04-10)
Primary citationJia, X.,Yan, X.,Mobli, M.,Qu, X.
The solution structure of abxF, an enzyme catalyzing the formation of chiral spiroketal of an antibiotics, (-)-ABX.
To Be Published,
Experimental method
SOLUTION NMR
Structure validation

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PDB entries from 2024-05-01

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