2MF3

SGTX-Sf1a

Summary for 2MF3

• Entry DOI: 10.2210/pdb2mf3/pdb
• NMR Information: BMRB: 19535
• Descriptor: U2-segestritoxin-Sf1a (1 entity in total)
• Functional Keywords: spider, toxin, ick, disulfide, non-uniform sampling, maximum entropy, insecticidal, heteronuclear
• Biological source: Segestria florentina (Tube-web spider)
• Cellular location: Secreted: P61095
• Total number of polymer chains: 1
• Total formula weight: 5073.92

Authors

Mobli, M.,Bende, N.S.,King, G.F. (deposition date: 2013-10-04, release date: 2014-10-15, Last modification date: 2023-06-14)

• Primary citation: Bende, N.S.,Dziemborowicz, S.,Herzig, V.,Ramanujam, V.,Brown, G.W.,Bosmans, F.,Nicholson, G.M.,King, G.F.,Mobli, M.; The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large beta-hairpin loop.; Febs J., 282:904-920, 2015; PubMed: 25559770; DOI: 10.1111/febs.13189

Experimental method

SOLUTION NMR