4UQK
 
 | | Electron density map of GluA2em in complex with quisqualate and LY451646 | | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2 | | 著者 | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | | 登録日 | 2014-06-24 | | 公開日 | 2014-08-13 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (16.4 Å) | | 主引用文献 | Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
|
|
4UQ6
 | | Electron density map of GluA2em in complex with LY451646 and glutamate | | 分子名称: | GLUTAMATE RECEPTOR 2, GLUTAMIC ACID | | 著者 | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | | 登録日 | 2014-06-20 | | 公開日 | 2014-08-13 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (12.8 Å) | | 主引用文献 | Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
|
|
4UQQ
 | | Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate | | 分子名称: | GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID | | 著者 | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | | 登録日 | 2014-06-24 | | 公開日 | 2014-08-13 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
|
|
4UQJ
 | | Cryo-EM density map of GluA2em in complex with ZK200775 | | 分子名称: | GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | | 著者 | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | | 登録日 | 2014-06-24 | | 公開日 | 2014-08-13 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (10.4 Å) | | 主引用文献 | Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
|
|
5KUF
 | | GluK2EM with 2S,4R-4-methylglutamate | | 分子名称: | 2S,4R-4-METHYLGLUTAMATE, Glutamate receptor ionotropic, kainate 2 | | 著者 | Meyerson, J.R, Chittori, S, Merk, A, Rao, P, Han, T.H, Serpe, M, Mayer, M.L, Subramaniam, S. | | 登録日 | 2016-07-13 | | 公開日 | 2016-09-07 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of kainate subtype glutamate receptor desensitization.
Nature, 537, 2016
|
|
5KUH
 | | GluK2EM with LY466195 | | 分子名称: | (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid, Glutamate receptor ionotropic, kainate 2 | | 著者 | Meyerson, J.R, Chittori, S, Merk, A, Rao, P, Han, T.H, Serpe, M, Mayer, M.L, Subramaniam, S. | | 登録日 | 2016-07-13 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (11.6 Å) | | 主引用文献 | Structural basis of kainate subtype glutamate receptor desensitization.
Nature, 537, 2016
|
|
7LVT
 | |
8DFL
 | |
7SSY
 | |
7SSX
 | | Structure of human Kv1.3 | | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion | | 著者 | Meyerson, J.R, Selvakumar, P. | | 登録日 | 2021-11-11 | | 公開日 | 2022-06-29 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
|
|
7SSZ
 | |
7SSV
 | | Structure of human Kv1.3 with Fab-ShK fusion | | 分子名称: | Fab-ShK fusion, heavy chain, light chain, ... | | 著者 | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | | 登録日 | 2021-11-11 | | 公開日 | 2022-06-29 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
|
|
7RFP
 | | Mouse GITR (mGITR) with DTA-1 Fab fragment | | 分子名称: | DTA-1 (heavy chain), DTA-1 (light chain), Tumor necrosis factor receptor superfamily member 18,Enhanced green fluorescent protein | | 著者 | Meyerson, J.R, He, C. | | 登録日 | 2021-07-14 | | 公開日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism.
Sci Adv, 8, 2022
|
|
7S0F
 | | Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi protein | | 分子名称: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y. | | 登録日 | 2021-08-30 | | 公開日 | 2021-11-17 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Structural basis and mechanism of activation of two different families of G proteins by the same GPCR.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7S0G
 | | Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi/s chimera protein | | 分子名称: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y. | | 登録日 | 2021-08-30 | | 公開日 | 2021-11-17 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | Structural basis and mechanism of activation of two different families of G proteins by the same GPCR.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7JJO
 | | Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor | | 分子名称: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Su, M, Zhu, L, Zhang, Y, Paknejad, N, Dey, R, Huang, J, Lee, M.Y, Williams, D, Jordan, K.D, Eng, E.T, Ernst, O.P, Meyerson, J.R, Hite, R.K, Walz, T, Liu, W, Huang, X.Y. | | 登録日 | 2020-07-27 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor.
Mol.Cell, 80, 2020
|
|
5CMM
 | |
5CMK
 | | Crystal structure of the GluK2EM LBD dimer assembly complex with glutamate and LY466195 | | 分子名称: | (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid, CHLORIDE ION, GLUTAMIC ACID, ... | | 著者 | Chittori, S, Mayer, M.L. | | 登録日 | 2015-07-16 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Structural basis of kainate subtype glutamate receptor desensitization.
Nature, 537, 2016
|
|
7URX
 | | SJ25C1 Fab in complex with soluble CD19 | | 分子名称: | B-lymphocyte antigen CD19, SJ25C1 Fab heavy chain, SJ25C1 Fab light chain | | 著者 | Meyerson, J, He, C. | | 登録日 | 2022-04-22 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | CD19 CAR antigen engagement mechanisms and affinity tuning.
Sci Immunol, 8, 2023
|
|
7URV
 | | FMC63 scFv in complex with soluble CD19 | | 分子名称: | B-lymphocyte antigen CD19, FMC63 single-chain variable fragment | | 著者 | Meyerson, J, He, C. | | 登録日 | 2022-04-22 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | CD19 CAR antigen engagement mechanisms and affinity tuning.
Sci Immunol, 8, 2023
|
|
7KS0
 | | GluK2/K5 with 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX) | | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | | 登録日 | 2020-11-20 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor.
Elife, 10, 2021
|
|
7KS3
 | | GluK2/K5 with L-Glu | | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | | 登録日 | 2020-11-20 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor.
Elife, 10, 2021
|
|
