8DFL

Structure of human Kv1.3 with A0194009G09 nanobodies (alternate conformation)

Summary for 8DFL

• Entry DOI: 10.2210/pdb8dfl/pdb
• EMDB information: 25417
• Descriptor: Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion, Nanobody A0194009G09, POTASSIUM ION (3 entities in total)
• Functional Keywords: ion channel, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 435589.09

Authors

Meyerson, J.R.,Selvakumar, P. (deposition date: 2022-06-22, release date: 2022-07-13, Last modification date: 2024-05-01)

• Primary citation: Selvakumar, P.,Fernandez-Marino, A.I.,Khanra, N.,He, C.,Paquette, A.J.,Wang, B.,Huang, R.,Smider, V.V.,Rice, W.J.,Swartz, K.J.,Meyerson, J.R.; Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.; Nat Commun, 13:3854-3854, 2022; PubMed: 35788586; DOI: 10.1038/s41467-022-31285-5

Experimental method

ELECTRON MICROSCOPY (3.25 Å)