2E2D
| Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2 | 分子名称: | CALCIUM ION, Matrix metallopeptidase 13, Metalloproteinase inhibitor 2, ... | 著者 | Maskos, K, Lang, R, Tschesche, H, Bode, W. | 登録日 | 2006-11-11 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Flexibility and Variability of TIMP Binding: X-ray Structure of the Complex Between Collagenase-3/MMP-13 and TIMP-2 J.Mol.Biol., 366, 2007
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1BKC
| CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE) | 分子名称: | N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME, ZINC ION | 著者 | Maskos, K, Fernandez-Catalan, C, Bode, W. | 登録日 | 1998-04-23 | 公開日 | 1999-06-22 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme. Proc.Natl.Acad.Sci.USA, 95, 1998
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1Q2L
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1UWY
| Crystal structure of human carboxypeptidase M | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE M, ZINC ION | 著者 | Maskos, K, Reverter, D, Bode, W. | 登録日 | 2004-02-17 | 公開日 | 2004-04-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of Human Carboxypeptidase M, a Membrane-Bound Enzyme that Regulates Peptide Hormone Activity J.Mol.Biol., 338, 2004
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3C7X
| Hemopexin-like domain of matrix metalloproteinase 14 | 分子名称: | CHLORIDE ION, Matrix metalloproteinase-14, SODIUM ION | 著者 | Tochowicz, A, Itoh, Y, Maskos, K, Bode, W, Goettig, P. | 登録日 | 2008-02-08 | 公開日 | 2009-02-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions J.Biol.Chem., 286, 2011
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2QZW
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3TG6
| Crystal Structure of Influenza A Virus nucleoprotein with Ligand | 分子名称: | Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-chloropyridin-3-yl)-5-methyl-1,2-oxazol-4-yl]methanone | 著者 | Pearce, B.C, Lewis, H.A, McDonnell, P.A, Steinbacher, S, Kiefersauer, R, Mortl, M, Maskos, K, Edavettal, S, Baldwin, E.T, Langley, D.R. | 登録日 | 2011-08-17 | 公開日 | 2012-08-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors To be Published
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4F7S
| Crystal structure of human CDK8/CYCC in the DMG-in conformation | 分子名称: | 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-16 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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5HVY
| CDK8/CYCC IN COMPLEX WITH COMPOUND 20 | 分子名称: | CHLORIDE ION, Cyclin-C, Cyclin-dependent kinase 8, ... | 著者 | Kiefer, J.R, Schneider, E.V, Maskos, K, Bergeron, P, Koehler, M. | 登録日 | 2016-01-28 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8. Acs Med.Chem.Lett., 7, 2016
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6B8A
| Crystal structure of MvfR ligand binding domain in complex with M64 | 分子名称: | 2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide, COBALT HEXAMMINE(III), DNA-binding transcriptional regulator | 著者 | Kitao, T, Steinbacher, S, Maskos, K, Blaesse, M, Rahme, L.G. | 登録日 | 2017-10-05 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Molecular Insights into Function and Competitive Inhibition ofPseudomonas aeruginosaMultiple Virulence Factor Regulator. MBio, 9, 2018
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3CKI
| Crystal structure of the TACE-N-TIMP-3 complex | 分子名称: | ADAM 17, Metalloproteinase inhibitor 3, SODIUM ION, ... | 著者 | Wisniewska, M, Goettig, P, Maskos, K, Belouski, E, Winters, D, Hecht, R, Black, R, Bode, W. | 登録日 | 2008-03-15 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex. J.Mol.Biol., 381, 2008
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6FXN
| Crystal structure of human BAFF in complex with Fab fragment of anti-BAFF antibody belimumab | 分子名称: | Tumor necrosis factor ligand superfamily member 13B, belimumab heavy chain, belimumab light chain | 著者 | Lammens, A, Maskos, K, Willen, L, Jiang, X, Schneider, P. | 登録日 | 2018-03-09 | 公開日 | 2018-04-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors. Nat Commun, 9, 2018
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3LU8
| Human serum albumin in complex with compound 3 | 分子名称: | N-[5-(5-{[(2,4-dimethyl-1,3-thiazol-5-yl)sulfonyl]amino}-6-fluoropyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]acetamide, Serum albumin | 著者 | Buttar, D, Colclough, N, Gerhardt, S, MacFaul, P.A, Phillips, S.D, Plowright, A, Whittamore, P, Tam, K, Maskos, K, Steinbacher, S, Steuber, H. | 登録日 | 2010-02-17 | 公開日 | 2010-10-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions Bioorg.Med.Chem., 18, 2010
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3LU6
| Human serum albumin in complex with compound 1 | 分子名称: | Serum albumin, [(1R,2R)-2-{[(5-fluoro-1H-indol-2-yl)carbonyl]amino}-2,3-dihydro-1H-inden-1-yl]acetic acid | 著者 | Buttar, D, Colclough, N, Gerhardt, S, MacFaul, P.A, Phillips, S.D, Plowright, A, Whittamore, P, Tam, K, Maskos, K, Steinbacher, S, Steuber, H. | 登録日 | 2010-02-17 | 公開日 | 2010-10-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions Bioorg.Med.Chem., 18, 2010
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3LU7
| Human serum albumin in complex with compound 2 | 分子名称: | 4-[(1R,2R)-2-{[(5-fluoro-1H-indol-2-yl)carbonyl]amino}-2,3-dihydro-1H-inden-1-yl]butanoic acid, PHOSPHATE ION, Serum albumin | 著者 | Buttar, D, Colclough, N, Gerhardt, S, MacFaul, P.A, Phillips, S.D, Plowright, A, Whittamore, P, Tam, K, Maskos, K, Steinbacher, S, Steuber, H. | 登録日 | 2010-02-17 | 公開日 | 2010-10-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions Bioorg.Med.Chem., 18, 2010
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3V3K
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5CEI
| Crystal structure of CDK8:Cyclin C complex with compound 22 | 分子名称: | 1,2-ETHANEDIOL, 4-(4-iodophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide, Cyclin-C, ... | 著者 | Kiefer, J.R, Schneider, E.V, Maskos, K, Koehler, M.F.T. | 登録日 | 2015-07-06 | 公開日 | 2016-02-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells. Acs Med.Chem.Lett., 7, 2016
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2QZX
| Secreted aspartic proteinase (Sap) 5 from Candida albicans | 分子名称: | Candidapepsin-5, Pepstatin | 著者 | Lee, J.H, Ruge, E, Borelli, C, Maskos, K, Huber, R. | 登録日 | 2007-08-17 | 公開日 | 2008-07-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | X-ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from Candida albicans. Proteins, 72, 2008
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3HGT
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3HGQ
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1GTL
| The thermostable serine-carboxyl type proteinase, kumamolisin (KSCP) - complex with Ac-Ile-Pro-Phe-cho | 分子名称: | ALDEHYDE INHIBITOR, CALCIUM ION, KUMAMOLYSIN, ... | 著者 | Comellas-Bigler, M, Fuentes-Prior, P, Maskos, K, Huber, R, Oyama, H, Uchida, K, Dunn, B.M, Oda, K, Bode, W. | 登録日 | 2002-01-16 | 公開日 | 2002-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase Structure, 10, 2002
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1GT9
| High resolution crystal structure of a thermostable serine-carboxyl type proteinase, kumamolisin (kscp) | 分子名称: | CALCIUM ION, KUMAMOLYSIN, SULFATE ION | 著者 | Comellas-Bigler, M, Fuentes-Prior, P, Maskos, K, Huber, R, Oyama, H, Uchida, K, Dunn, B.M, Oda, K, Bode, W. | 登録日 | 2002-01-14 | 公開日 | 2002-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase Structure, 10, 2002
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3RO5
| Crystal structure of influenza A virus nucleoprotein with ligand | 分子名称: | Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]methanone | 著者 | Pearce, B.C, Edavettal, S, McDonnell, P.A, Lewis, H.A, Steinbacher, S, Baldwin, E.T, Langley, D.R, Maskos, K, Mortl, M, Kiefersauer, R. | 登録日 | 2011-04-25 | 公開日 | 2011-09-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers. Proc.Natl.Acad.Sci.USA, 108, 2011
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3RGF
| Crystal Structure of human CDK8/CycC | 分子名称: | 1,2-ETHANEDIOL, 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Cyclin-C, ... | 著者 | Schneider, E.V, Boettcher, J, Blaesse, M, Huber, R, Maskos, K. | 登録日 | 2011-04-08 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder. J.Mol.Biol., 412, 2011
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2H6T
| Secreted aspartic proteinase (Sap) 3 from Candida albicans complexed with pepstatin A | 分子名称: | Candidapepsin-3, ZINC ION, pepstatin A | 著者 | Ruge, E, Borelli, C, Maskos, K, Huber, R. | 登録日 | 2006-06-01 | 公開日 | 2007-06-12 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A. Proteins, 68, 2007
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