3RGF
Crystal Structure of human CDK8/CycC
Summary for 3RGF
Entry DOI | 10.2210/pdb3rgf/pdb |
Descriptor | Cyclin-dependent kinase 8, Cyclin-C, 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, ... (6 entities in total) |
Functional Keywords | protein kinase complex, transferase, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): P49336 P24863 |
Total number of polymer chains | 2 |
Total formula weight | 81710.42 |
Authors | Schneider, E.V.,Boettcher, J.,Blaesse, M.,Huber, R.,Maskos, K. (deposition date: 2011-04-08, release date: 2011-08-10, Last modification date: 2023-09-13) |
Primary citation | Schneider, E.V.,Bottcher, J.,Blaesse, M.,Neumann, L.,Huber, R.,Maskos, K. The Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder. J.Mol.Biol., 412:251-266, 2011 Cited by PubMed: 21806996DOI: 10.1016/j.jmb.2011.07.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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