Crystal structure of MvfR ligand binding domain in complex with M64

Summary for 6B8A

DescriptorDNA-binding transcriptional regulator, 2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide, COBALT HEXAMMINE(III), ... (4 entities in total)
Functional Keywordsmvfr transcriptional regulator, pqsr, transcription
Biological sourcePseudomonas aeruginosa
Total number of polymer chains2
Total molecular weight46712.82
Kitao, T.,Steinbacher, S.,Maskos, K.,Blaesse, M.,Rahme, L.G. (deposition date: 2017-10-05, release date: 2018-01-31, Last modification date: 2019-12-11)
Primary citation
Kitao, T.,Lepine, F.,Babloudi, S.,Walte, F.,Steinbacher, S.,Maskos, K.,Blaesse, M.,Negri, M.,Pucci, M.,Zahler, B.,Felici, A.,Rahme, L.G.
Molecular Insights into Function and Competitive Inhibition ofPseudomonas aeruginosaMultiple Virulence Factor Regulator.
MBio, 9:-, 2018
PubMed: 29339431 (PDB entries with the same primary citation)
DOI: 10.1128/mBio.02158-17
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24211.5%2.0%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16