3TG6

Crystal Structure of Influenza A Virus nucleoprotein with Ligand

Summary for 3TG6

• Entry DOI: 10.2210/pdb3tg6/pdb
• Descriptor: Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-chloropyridin-3-yl)-5-methyl-1,2-oxazol-4-yl]methanone (3 entities in total)
• Functional Keywords: influenza nucleoprotein, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Influenza A virus
• Total number of polymer chains: 2
• Total formula weight: 114536.67

Authors

Pearce, B.C.,Lewis, H.A.,McDonnell, P.A.,Steinbacher, S.,Kiefersauer, R.,Mortl, M.,Maskos, K.,Edavettal, S.,Baldwin, E.T.,Langley, D.R. (deposition date: 2011-08-17, release date: 2012-08-29, Last modification date: 2024-02-28)

• Primary citation: Edavettal, S.C.,Pearce, B.C.,Lewis, H.A.,Schneeweis, L.,Deminie, C.,Discotto, L.,Carpenter, B.,Yanchunas, J.,Langley, D.R.,Metzler, W.,Gao, M.,Poss, M.A.,Maskos, K.,Mortl, M.,Keifersauer, R.,Steinbacher, S.,Healy, M.,Phillip, T.,Zoeckler, M.,Schartman, R.,McAuliffe, B.,Minassian, B.F.,Shi, S.,Zhu, S.,Pendri, A.,Li, G.,Sinz, M.,Meanwell, N.A.,Krystal, M.,Gerritz, S.W.,Cianci, C.,Baldwin, B.T.,Bryson, J.W.,McDonnell, P.A.; Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)