4GLN
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![BU of 4gln by Molmil](/molmil-images/mine/4gln) | Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21/n | Descriptor: | D-RFX001, Vascular endothelial growth factor A | Authors: | Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H. | Deposit date: | 2012-08-14 | Release date: | 2012-09-05 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography. Proc.Natl.Acad.Sci.USA, 109, 2012
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4GLU
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![BU of 4glu by Molmil](/molmil-images/mine/4glu) | Crystal structure of the mirror image form of VEGF-A | Descriptor: | ACETATE ION, D- Vascular endothelial growth factor-A, GLYCEROL, ... | Authors: | Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H. | Deposit date: | 2012-08-14 | Release date: | 2012-09-05 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography. Proc.Natl.Acad.Sci.USA, 109, 2012
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4GLS
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![BU of 4gls by Molmil](/molmil-images/mine/4gls) | Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21 | Descriptor: | D- RFX001, D- Vascular endothelial growth factor-A, DI(HYDROXYETHYL)ETHER, ... | Authors: | Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H. | Deposit date: | 2012-08-14 | Release date: | 2012-09-05 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography. Proc.Natl.Acad.Sci.USA, 109, 2012
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3QTK
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![BU of 3qtk by Molmil](/molmil-images/mine/3qtk) | The crystal structure of chemically synthesized VEGF-A | Descriptor: | ACETATE ION, GLYCEROL, Vascular endothelial growth factor A, ... | Authors: | Mandal, K, Kent, S.B.H. | Deposit date: | 2011-02-22 | Release date: | 2011-07-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Total chemical synthesis of biologically active vascular endothelial growth factor. Angew.Chem.Int.Ed.Engl., 50, 2011
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3UE7
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![BU of 3ue7 by Molmil](/molmil-images/mine/3ue7) | X-ray crystal structure of a novel topological analogue of crambin | Descriptor: | Crambin, D-Crambin | Authors: | Mandal, K, Pentelute, B.L, Bang, D, Gates, Z.P, Torbeev, V.Y, Kent, S.B.H. | Deposit date: | 2011-10-28 | Release date: | 2012-02-08 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Design, total chemical synthesis, and x-ray structure of a protein having a novel linear-loop polypeptide chain topology. Angew.Chem.Int.Ed.Engl., 51, 2012
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3E7U
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![BU of 3e7u by Molmil](/molmil-images/mine/3e7u) | X-ray Crystal Structure of L-Plectasin | Descriptor: | Plectasin | Authors: | Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H. | Deposit date: | 2008-08-18 | Release date: | 2009-06-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods Protein Sci., 18, 2009
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3E7R
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![BU of 3e7r by Molmil](/molmil-images/mine/3e7r) | X-ray Crystal Structure of Racemic Plectasin | Descriptor: | Plectasin | Authors: | Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H. | Deposit date: | 2008-08-18 | Release date: | 2009-06-09 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods Protein Sci., 18, 2009
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3E8Y
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![BU of 3e8y by Molmil](/molmil-images/mine/3e8y) | Xray structure of scorpion toxin BmBKTx1 | Descriptor: | CHLORIDE ION, Potassium channel toxin alpha-KTx 19.1, SULFATE ION | Authors: | Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H. | Deposit date: | 2008-08-20 | Release date: | 2009-02-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods. J.Am.Chem.Soc., 131, 2009
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5EN9
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![BU of 5en9 by Molmil](/molmil-images/mine/5en9) | High resolution x-ray crystal structure of isotope-labeled ester-insulin | Descriptor: | Insulin chain A, Insulin chain B | Authors: | Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. | Deposit date: | 2015-11-09 | Release date: | 2016-01-13 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016
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5ENA
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![BU of 5ena by Molmil](/molmil-images/mine/5ena) | Xray crystal structure of isotope-labeled human insulin | Descriptor: | Insulin chain A, Insulin chain B | Authors: | Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. | Deposit date: | 2015-11-09 | Release date: | 2016-01-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016
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5UDP
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![BU of 5udp by Molmil](/molmil-images/mine/5udp) | High resolution x-ray crystal structure of synthetic insulin lispro | Descriptor: | CHLORIDE ION, Insulin Lispro A chain, Insulin Lispro B chain, ... | Authors: | Mandal, K, Dhayalan, B, Kent, S.B.H. | Deposit date: | 2016-12-28 | Release date: | 2017-01-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.348 Å) | Cite: | Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin. Chemistry, 23, 2017
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5HHD
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![BU of 5hhd by Molmil](/molmil-images/mine/5hhd) | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21 | Descriptor: | D-Peptide RFX037.D, D-Vascular endothelial growth factor, DI(HYDROXYETHYL)ETHER, ... | Authors: | Uppalapati, M, LEE, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | Deposit date: | 2016-01-10 | Release date: | 2016-03-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. Acs Chem.Biol., 11, 2016
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5I5B
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![BU of 5i5b by Molmil](/molmil-images/mine/5i5b) | quasi racemic structure of allo-Thr13-ShK and D-ShK | Descriptor: | D-ShK, GLYCEROL, Kappa-stichotoxin-She3a, ... | Authors: | Dang, B, Kubota, T, Mandal, K, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | Deposit date: | 2016-02-15 | Release date: | 2017-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew. Chem. Int. Ed. Engl., 56, 2017
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6LFH
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![BU of 6lfh by Molmil](/molmil-images/mine/6lfh) | |
5CY0
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![BU of 5cy0 by Molmil](/molmil-images/mine/5cy0) | Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography | Descriptor: | GLYCEROL, Ts3 Toxin | Authors: | Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B. | Deposit date: | 2015-07-29 | Release date: | 2016-06-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angew.Chem.Int.Ed.Engl., 55, 2016
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4WSP
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![BU of 4wsp by Molmil](/molmil-images/mine/4wsp) | Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-I) | Descriptor: | CHLORIDE ION, protein DL-Rv1738 | Authors: | Bunker, R.D, Mandal, K, Kent, S.B.H, Baker, E.N. | Deposit date: | 2014-10-28 | Release date: | 2015-03-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4WPY
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![BU of 4wpy by Molmil](/molmil-images/mine/4wpy) | Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-II) | Descriptor: | GLYCEROL, protein DL-Rv1738, trifluoroacetic acid | Authors: | Bunker, R.D, Mandal, K, Kent, S.B.H, Baker, E.N. | Deposit date: | 2014-10-21 | Release date: | 2015-03-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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5I5A
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![BU of 5i5a by Molmil](/molmil-images/mine/5i5a) | quasi racemic structure of allo-Ile7-ShK and D-ShK | Descriptor: | D-MALATE, D-ShK, GLYCEROL, ... | Authors: | Dang, B, Kubota, T, Mandal, K, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | Deposit date: | 2016-02-14 | Release date: | 2017-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew. Chem. Int. Ed. Engl., 56, 2017
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3NGG
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![BU of 3ngg by Molmil](/molmil-images/mine/3ngg) | X-ray Structure of Omwaprin | Descriptor: | Omwaprin-a | Authors: | Banigan, J.R, Mandal, K, Sawaya, M.R, Thammavongsa, V, Hendrickx, A.P.A, Schneewind, O, Yeates, T.O, Kent, S.B.H. | Deposit date: | 2010-06-11 | Release date: | 2010-09-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Protein Sci., 19, 2010
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3ODV
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![BU of 3odv by Molmil](/molmil-images/mine/3odv) | X-ray structure of kaliotoxin by racemic protein crystallography | Descriptor: | CITRIC ACID, Potassium channel toxin alpha-KTx 3.1, trifluoroacetic acid | Authors: | Pentelute, B.L, Mandal, K, Gates, Z.P, Sawaya, M.R, Yeates, T.O, Kent, S.B.H. | Deposit date: | 2010-08-11 | Release date: | 2010-10-20 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Chem.Commun.(Camb.), 46, 2010
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4IUZ
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![BU of 4iuz by Molmil](/molmil-images/mine/4iuz) | High resolution crystal structure of racemic ester insulin | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ... | Authors: | Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H. | Deposit date: | 2013-01-22 | Release date: | 2013-02-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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4LFQ
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![BU of 4lfq by Molmil](/molmil-images/mine/4lfq) | High resolution x-ray crystal structure of L-ShK toxin | Descriptor: | Potassium channel toxin ShK | Authors: | Dang, B, Kubota, T, Mandal, K, Bezanilla, F, Kent, S.B.H. | Deposit date: | 2013-06-27 | Release date: | 2013-08-14 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.059 Å) | Cite: | Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High-Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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4LFS
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![BU of 4lfs by Molmil](/molmil-images/mine/4lfs) | High resolution x-ray structure of racemic ShK toxin | Descriptor: | CHLORIDE ION, GLYCEROL, Potassium channel toxin ShK | Authors: | Dang, B, Kubota, T, Mandal, K, Bezanilla, F, Kent, S.B.H. | Deposit date: | 2013-06-27 | Release date: | 2013-08-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High-Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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4OIK
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![BU of 4oik by Molmil](/molmil-images/mine/4oik) | (Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ... | Authors: | Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. | Deposit date: | 2014-01-19 | Release date: | 2014-05-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
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4OIJ
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![BU of 4oij by Molmil](/molmil-images/mine/4oij) | X-ray crystal structure of racemic non-glycosylated chemokine Ser-CCL1 | Descriptor: | C-C motif chemokine 1, D-Ser-CCL1, SULFATE ION | Authors: | Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. | Deposit date: | 2014-01-19 | Release date: | 2014-05-07 | Last modified: | 2014-05-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
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