8GZ2
| Cryo-EM structure of human NaV1.6/beta1/beta2-4,9-anhydro-tetrodotoxin | Descriptor: | (1R,2S,3S,4R,5R,9S,11S,12S,14R)-7-amino-2,4,12-trihydroxy-2-(hydroxymethyl)-10,13,15-trioxa-6,8-diazapentacyclo[7.4.1.1~3,12~.0~5,11~.0~5,14~]pentadec-7-en-8-ium (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 8 subunit alpha, ... | Authors: | Li, Y, Jiang, D. | Deposit date: | 2022-09-24 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of human Na V 1.6 channel reveals Na + selectivity and pore blockade by 4,9-anhydro-tetrodotoxin. Nat Commun, 14, 2023
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1KQL
| Crystal structure of the C-terminal region of striated muscle alpha-tropomyosin at 2.7 angstrom resolution | Descriptor: | Fusion Protein of and striated muscle alpha-tropomyosin and the GCN4 leucine zipper | Authors: | Li, Y, Mui, S, Brown, J.H, Strand, J, Reshetnikova, L, Tobacman, L.S, Cohen, C. | Deposit date: | 2002-01-07 | Release date: | 2002-05-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site. Proc.Natl.Acad.Sci.USA, 99, 2002
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1KGD
| Crystal Structure of the Guanylate Kinase-like Domain of Human CASK | Descriptor: | FORMIC ACID, PERIPHERAL PLASMA MEMBRANE CASK | Authors: | Li, Y, Spangenberg, O, Paarmann, I, Konrad, M, Lavie, A. | Deposit date: | 2001-11-26 | Release date: | 2001-12-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.314 Å) | Cite: | Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains. J.Biol.Chem., 277, 2002
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1XGP
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1XGT
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1XGQ
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1NKN
| VISUALIZING AN UNSTABLE COILED COIL: THE CRYSTAL STRUCTURE OF AN N-TERMINAL SEGMENT OF THE SCALLOP MYOSIN ROD | Descriptor: | S2N51-GCN4 | Authors: | Li, Y, Brown, J.H, Reshetnikova, L, Blazsek, A, Farkas, L, Nyitray, L, Cohen, C. | Deposit date: | 2003-01-03 | Release date: | 2003-07-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Visualization of an unstable coiled coil from the scallop myosin rod Nature, 424, 2003
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1ZGL
| Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, Myelin basic protein, ... | Authors: | Li, Y, Huang, Y, Lue, J, Quandt, J.A, Martin, R, Mariuzza, R.A. | Deposit date: | 2005-04-21 | Release date: | 2005-10-18 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule. Embo J., 24, 2005
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3HHS
| Crystal Structure of Manduca sexta prophenoloxidase | Descriptor: | COPPER (II) ION, Phenoloxidase subunit 1, Phenoloxidase subunit 2 | Authors: | Li, Y, Wang, Y, Jiang, H, Deng, J. | Deposit date: | 2009-05-17 | Release date: | 2009-09-29 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of Manduca sexta prophenoloxidase provides insights into the mechanism of type 3 copper enzymes. Proc.Natl.Acad.Sci.USA, 106, 2009
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8GPX
| YFV_E_YD73Fab_postfusion | Descriptor: | Envelope protein, YD73Fab_H, YD73Fab_K | Authors: | Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F. | Deposit date: | 2022-08-27 | Release date: | 2022-11-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus. Innovation (N Y), 3, 2022
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5DO2
| Complex structure of MERS-RBD bound with 4C2 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C2 heavy chain, 4C2 light chain, ... | Authors: | Li, Y, Wan, Y, Liu, P, Zhao, J, Lu, G, Qi, J, Wang, Q, Lu, X, Wu, Y, Liu, W, Yuen, K.Y, Perlman, S, Gao, G.F, Yan, J. | Deposit date: | 2015-09-10 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.409 Å) | Cite: | A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Res., 25, 2015
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3JBB
| Characterization of red-shifted phycobiliprotein complexes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris | Descriptor: | PHYCOCYANOBILIN, SULFATE ION, allophycocyanin beta chain, ... | Authors: | Li, Y, Lin, Y, Garvey, C, Birch, D, Corkery, R.W, Loughlin, P.C, Scheer, H, Willows, R.D, Chen, M. | Deposit date: | 2015-08-26 | Release date: | 2015-11-11 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (26 Å) | Cite: | Characterization of red-shifted phycobilisomes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris. Biochim.Biophys.Acta, 1857, 2015
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1SL2
| Ternary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template and an incoming nucleotide | Descriptor: | 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*TP*(2DA))-3', ... | Authors: | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | Deposit date: | 2004-03-05 | Release date: | 2004-07-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
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1SKW
| Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template | Descriptor: | 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ... | Authors: | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | Deposit date: | 2004-03-05 | Release date: | 2004-07-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
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1SL1
| Binary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template | Descriptor: | 5'-D(*CP*CP*C*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*TP*(2DA))-3', DNA polymerase, ... | Authors: | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | Deposit date: | 2004-03-05 | Release date: | 2004-07-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
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1SKS
| Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template | Descriptor: | 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ... | Authors: | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | Deposit date: | 2004-03-05 | Release date: | 2004-07-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
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4XVJ
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3KEA
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6N1I
| Cryo-EM structure of NLRC4-CARD filament | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Li, Y, Fu, T, Wu, H. | Deposit date: | 2018-11-08 | Release date: | 2018-12-05 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6O59
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8GPT
| YFV_E_YD6scFv_postfusion | Descriptor: | Envelope protein, YD6_VH, YD6_VL | Authors: | Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F. | Deposit date: | 2022-08-27 | Release date: | 2022-11-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus. Innovation (N Y), 3, 2022
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8GPU
| YFV_E_YD6Fab_prefusion | Descriptor: | Envelope protein, YD6Fab_H, YD6Fab_L | Authors: | Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F. | Deposit date: | 2022-08-27 | Release date: | 2022-11-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus. Innovation (N Y), 3, 2022
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3D34
| Structure of the F-spondin domain of mindin | Descriptor: | CALCIUM ION, NICKEL (II) ION, Spondin-2 | Authors: | Li, Y, Mariuzza, R.A. | Deposit date: | 2008-05-09 | Release date: | 2009-02-17 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule. Embo J., 28, 2009
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8JOL
| cryo-EM structure of the CED-4/CED-3 holoenzyme | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 3, Cell death protein 4, ... | Authors: | Li, Y, Tian, L, Zhang, Y, Shi, Y. | Deposit date: | 2023-06-07 | Release date: | 2023-06-28 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into CED-3 activation. Life Sci Alliance, 6, 2023
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5FNA
| Cryo-EM reconstruction of caspase-1 CARD | Descriptor: | Caspase-1 | Authors: | Li, Y, Lu, A, Schmidt, F.I, Yin, Q, Chen, S, Fu, T.M, Tong, A.B, Ploegh, H.L, Mao, Y, Wu, H. | Deposit date: | 2015-11-11 | Release date: | 2016-03-30 | Last modified: | 2019-09-11 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism Nat.Struct.Mol.Biol., 23, 2016
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