7S07
| Crystal structure of Epstein-Barr virus glycoprotein gH/gL/gp42-peptide in complex with human neutralizing antibodies 769B10 and 769C2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 769B10 Fab heavy chain, 769B10 Fab light chain, ... | Authors: | Chen, W.-H, Kanekiyo, M, Cohen, J.I, Joyce, M.G. | Deposit date: | 2021-08-30 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition. Immunity, 55, 2022
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7S0J
| Crystal structure of Epstein-Barr virus gH/gL targeting antibody 769B10 | Descriptor: | 769B10 Fab Heavy chain, 769B10 Fab Light chain, GLYCEROL | Authors: | Chen, W.-H, Kanekiyo, M, Cohen, J.I, Joyce, M.G. | Deposit date: | 2021-08-30 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition. Immunity, 55, 2022
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7S08
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3UPZ
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3UQF
| c-SRC kinase domain in complex with BKI RM-1-89 | Descriptor: | 3-(6-ethoxynaphthalen-2-yl)-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src | Authors: | Merritt, E.A, Larson, E.T. | Deposit date: | 2011-11-20 | Release date: | 2012-03-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
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3UQG
| c-SRC kinase domain in complex with bumpless BKI analog UW1243 | Descriptor: | 1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src | Authors: | Merritt, E.A, Larson, E.T. | Deposit date: | 2011-11-20 | Release date: | 2012-03-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
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3V5T
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3V51
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3V5P
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3UPX
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5F8E
| Rv2258c-SAH | Descriptor: | Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Im, H.N, Suh, S.W. | Deposit date: | 2015-12-09 | Release date: | 2016-06-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of Rv2258c from Mycobacterium tuberculosis H37Rv, an S-adenosyl-l-methionine-dependent methyltransferase J.Struct.Biol., 193, 2016
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5F8C
| Rv2258c-unbound | Descriptor: | GLYCEROL, Methyltransferase | Authors: | Im, H.N, Suh, S.W. | Deposit date: | 2015-12-09 | Release date: | 2016-06-29 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal structure of Rv2258c from Mycobacterium tuberculosis H37Rv, an S-adenosyl-l-methionine-dependent methyltransferase J.Struct.Biol., 193, 2016
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5F8F
| Rv2258c-SFG | Descriptor: | GLYCEROL, Methyltransferase, SINEFUNGIN | Authors: | Im, H.N, Suh, S.W. | Deposit date: | 2015-12-09 | Release date: | 2016-06-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Rv2258c from Mycobacterium tuberculosis H37Rv, an S-adenosyl-l-methionine-dependent methyltransferase J.Struct.Biol., 193, 2016
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5UIX
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5WW0
| Crystal structure of Set7, a novel histone methyltransferase in Schizossacharomyces pombe | Descriptor: | SET domain-containing protein 7, SULFATE ION | Authors: | Mevius, D.E.H.F, Shen, Y, Morishita, M, Carrozzini, B, Caliandro, R, di Luccio, E. | Deposit date: | 2016-12-30 | Release date: | 2017-12-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis. Structure, 27, 2019
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2MBC
| Solution Structure of human holo-PRL-3 in complex with vanadate | Descriptor: | Protein tyrosine phosphatase type IVA 3 | Authors: | Jeong, K, Kang, D, Kim, J, Shin, S, Jin, B, Lee, C, Kim, E, Jeon, Y.H, Kim, Y. | Deposit date: | 2013-07-29 | Release date: | 2013-10-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure and backbone dynamics of vanadate-bound PRL-3: comparison of 15N nuclear magnetic resonance relaxation profiles of free and vanadate-bound PRL-3. Biochemistry, 53, 2014
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8PM2
| Structure of the murine trace amine-associated receptor TAAR7f bound to N,N-dimethylcyclohexylamine (DMCH) in complex with mini-Gs trimeric G protein | Descriptor: | CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Gusach, A, Lee, Y, Edwards, P.C, Huang, F, Weyand, S.N, Tate, C.G. | Deposit date: | 2023-06-28 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f. Biorxiv, 2023
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2OO8
| Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors | Descriptor: | Angiopoietin-1 receptor, N-{3-[3-(DIMETHYLAMINO)PROPYL]-5-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]BENZAMIDE | Authors: | Bellon, S.F, Kim, J. | Deposit date: | 2007-01-25 | Release date: | 2007-03-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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2OSC
| Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors | Descriptor: | Angiopoietin-1 receptor, N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE | Authors: | Bellon, S.F, Kim, J. | Deposit date: | 2007-02-05 | Release date: | 2007-03-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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3SX9
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2J7Z
| Crystal Structure of recombinant Human Stromal Cell-Derived Factor- 1alpha | Descriptor: | STROMAL CELL-DERIVED FACTOR 1 ALPHA | Authors: | Ryu, E.K, Kim, T.G, Kwon, T.H, Jung, I.D, Ryu, D.W, Park, Y.-M, Ahn, K, Ban, C. | Deposit date: | 2006-10-18 | Release date: | 2006-10-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of Recombinant Human Stromal Cell-Derived Factor-1Alpha. Proteins, 67, 2007
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5V7U
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5V7R
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8E90
| Inhibition of Human Menin by SNDX-5613 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, ... | Authors: | McKeever, B.M, KULKARNI, S, McGeehan, G.M. | Deposit date: | 2022-08-26 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | MEN1 mutations mediate clinical resistance to menin inhibition. Nature, 615, 2023
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1KOZ
| SOLUTION STRUCTURE OF OMEGA-GRAMMOTOXIN SIA | Descriptor: | Voltage-dependent Channel Inhibitor | Authors: | Takeuchi, K, Park, E.J, Lee, C.W, Kim, J.I, Takahashi, H, Swartz, K.J, Shimada, I. | Deposit date: | 2001-12-25 | Release date: | 2002-08-28 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel. J.Mol.Biol., 321, 2002
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