3EGS
| Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671 soaked in ammonium sulfate | 分子名称: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, gp41 scrFP-MPER construct | 著者 | Julien, J.-P, Bryson, S, de la Torre, B.G, Andreu, D, Nieva, J.L, Pai, E.F. | 登録日 | 2008-09-11 | 公開日 | 2009-08-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5. J.Phys.Chem.B, 113, 2009
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5D9Q
| Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Julien, J.-P, Stanfield, R.L, Ward, A.B, Wilson, I.A. | 登録日 | 2015-08-18 | 公開日 | 2016-08-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathog., 12, 2016
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4NPY
| Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody | 分子名称: | GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain | 著者 | Julien, J.-P, Diwanji, D.C, Wilson, I.A. | 登録日 | 2013-11-22 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | 主引用文献 | The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies. Plos Pathog., 9, 2013
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4JPJ
| Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | 著者 | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | 登録日 | 2013-03-19 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
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4JPK
| Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain eOD-GT6 in complex with a putative VRC01 germline precursor Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6, ... | 著者 | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | 登録日 | 2013-03-19 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
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4JPI
| Crystal structure of a putative VRC01 germline precursor Fab | 分子名称: | GLYCEROL, Putative VRC01 germline Fab heavy chain, Putative VRC01 germline Fab light chain | 著者 | Julien, J.-P, Diwanji, D.C, Jardine, J, Schief, W.R, Wilson, I.A. | 登録日 | 2013-03-19 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
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4LG2
| Crystal structure of Reston Ebola virus VP35 RNA binding domain bound to 12-bp dsRNA | 分子名称: | Polymerase cofactor, dsRNA | 著者 | Bale, S, Julien, J.-P, Bornholdt, Z.A, Krois, A.S, Wilson, I.A, Saphire, E.O. | 登録日 | 2013-06-27 | 公開日 | 2013-07-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism. J.Virol., 87, 2013
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3Q1S
| HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ... | 著者 | Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A. | 登録日 | 2010-12-17 | 公開日 | 2011-11-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope. J.Mol.Biol., 414, 2011
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8EUQ
| Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... | 著者 | Kassardjian, A, Julien, J.-P. | 登録日 | 2022-10-19 | 公開日 | 2023-04-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses. Cell Rep, 42, 2023
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4JM2
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4JM4
| Crystal Structure of PGT 135 Fab | 分子名称: | PGT 135 Heavy Chain, PGT 135 Light Chain | 著者 | Kong, L, Wilson, I.A. | 登録日 | 2013-03-13 | 公開日 | 2013-05-29 | 最終更新日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | 主引用文献 | Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat.Struct.Mol.Biol., 20, 2013
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3TV3
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3U1S
| Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody | 分子名称: | Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ... | 著者 | Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
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3TWC
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3TYG
| Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3) | 分子名称: | Envelope glycoprotein gp160, PGT128 heavy chain, Ig gamma-1 chain C region, ... | 著者 | Pejchal, R, Huang, P.S, Schief, W.R, Stanfield, R.L, Wilson, I.A. | 登録日 | 2011-09-25 | 公開日 | 2011-10-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science, 334, 2011
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4NUG
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4NUJ
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4R26
| Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | 分子名称: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | 著者 | Garces, F, Kong, L, Wilson, I.A. | 登録日 | 2014-08-08 | 公開日 | 2014-10-08 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (2.4969 Å) | 主引用文献 | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159, 2014
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4R2G
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2FNI
| PseC aminotransferase involved in pseudoaminic acid biosynthesis | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, aminotransferase | 著者 | Cygler, M, Matte, A, Lunin, V.V, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2006-01-11 | 公開日 | 2006-01-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori J.Biol.Chem., 281, 2006
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2FNU
| PseC aminotransferase with external aldimine | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, aminotransferase | 著者 | Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2006-01-11 | 公開日 | 2006-01-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori J.Biol.Chem., 281, 2006
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2FN6
| Helicobacter pylori PseC, aminotransferase involved in the biosynthesis of pseudoaminic acid | 分子名称: | AMINOTRANSFERASE, PHOSPHATE ION | 著者 | Cygler, M, Lunin, V.V, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2006-01-10 | 公開日 | 2006-01-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.483 Å) | 主引用文献 | Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori J.Biol.Chem., 281, 2006
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6S3D
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5IF0
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5IES
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