6FEQ
 
 | | Structure of inhibitor-bound ABCG2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. | | Deposit date: | 2018-01-03 | | Release date: | 2018-04-11 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat. Struct. Mol. Biol., 25, 2018
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6HIJ
 | | Cryo-EM structure of the human ABCG2-MZ29-Fab complex with cholesterol and PE lipids docked | | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ATP-binding cassette sub-family G member 2, CHOLESTEROL, ... | | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | | Deposit date: | 2018-08-30 | | Release date: | 2018-09-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat.Struct.Mol.Biol., 25, 2018
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6ETI
 | | Structure of inhibitor-bound ABCG2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. | | Deposit date: | 2017-10-26 | | Release date: | 2018-04-11 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat. Struct. Mol. Biol., 25, 2018
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6FFC
 | | Structure of an inhibitor-bound ABC transporter | | Descriptor: | ATP-binding cassette sub-family G member 2, ~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate | | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | | Deposit date: | 2018-01-06 | | Release date: | 2018-04-11 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat. Struct. Mol. Biol., 25, 2018
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8P8J
 | | Structure of 5D3-Fab and nanobody(Nb96)-bound ABCG2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | | Authors: | Irobalieva, R.N, Manolaridis, I, Jackson, S.M, Ni, D, Pardon, E, Stahlberg, H, Steyaert, J, Locher, K.P. | | Deposit date: | 2023-06-01 | | Release date: | 2023-08-30 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies.
J.Mol.Biol., 435, 2023
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8P7W
 | | Structure of 5D3-Fab and nanobody(Nb8)-bound ABCG2 | | Descriptor: | 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ATP-binding cassette sub-family G member 2, ... | | Authors: | Irobalieva, R.N, Manolaridis, I, Jackson, S.M, Ni, D, Pardon, E, Stahlberg, H, Steyaert, J, Locher, K.P. | | Deposit date: | 2023-05-31 | | Release date: | 2023-08-30 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies.
J.Mol.Biol., 435, 2023
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8P8A
 | | Structure of 5D3-Fab and nanobody(Nb17)-bound ABCG2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | | Authors: | Irobalieva, R.N, Manolaridis, I, Jackson, S.M, Ni, D, Pardon, E, Stahlberg, H, Steyaert, J, Locher, K.P. | | Deposit date: | 2023-05-31 | | Release date: | 2023-08-30 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies.
J.Mol.Biol., 435, 2023
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5NJ3
 | | Structure of an ABC transporter: complete structure | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | | Authors: | Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P. | | Deposit date: | 2017-03-28 | | Release date: | 2017-06-07 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
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7OJ8
 | | ABCG2 E1S turnover-2 state | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ... | | Authors: | Ni, D, Yu, Q, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | | Deposit date: | 2021-05-14 | | Release date: | 2021-07-21 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
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7OJH
 | | ABCG2 topotecan turnover-1 state | | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... | | Authors: | Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | | Deposit date: | 2021-05-15 | | Release date: | 2021-07-21 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
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7OJI
 | | ABCG2 topotecan turnover-2 state | | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... | | Authors: | Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | | Deposit date: | 2021-05-16 | | Release date: | 2021-07-21 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
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9HLD
 | | TRPML1 in complex with compound 13 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 1-[(8R,9S,13S,14S,17S)-13-methyl-17-oxidanyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl]ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HLA
 | | TRPML1 in complex with compound 9a | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HLB
 | | TRPML1 in complex with compound 10 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HJ8
 | | TRPML1 in complex with compound 5 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-11-28 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HLC
 | | TRPML1 in complex with compound 11 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, (8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HL3
 | | TRPML1 in complex with compound 1a | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-[2-oxidanylidene-2-[(4R)-2,2,4-trimethyl-3,4-dihydroquinolin-1-yl]ethyl]isoindole-1,3-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HJ6
 | | TRPML1 in complex with compound 2 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEXADECANE, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-11-28 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HL4
 | | TRPML1 in complex with compound 3 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HL6
 | | TRPML1 in complex with compound 4a | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[[(3R)-3-[1-(4-chloranyl-2-fluoranyl-phenyl)piperidin-4-yl]-3-methyl-2H-indol-1-yl]sulfonyl]-N,N-dimethyl-benzenesulfonamide, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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9HL8
 | | TRPML1 in complex with compound 8 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | | Authors: | Reeks, J, Mahajan, P, Clark, M, Cowan, S.R, Di Daniel, E, Earl, C.P, Fisher, S, Holvey, R.S, Jackson, S.M, Lloyd-Evans, E, Morgillo, C.M, Mortenson, P.N, O'Reilly, M, Richardson, C.J, Schopf, P, Tams, D.M, Waller-Evans, H, Ward, S.E, Whibley, S, Williams, P.A, Johnson, C.N. | | Deposit date: | 2024-12-04 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
To Be Published
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8Q7B
 | | ABCG2 in complex with MZ29 and 5D3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | | Authors: | Kowal, J, Yu, Q, Ni, D, Stahlberg, H, Tajkhorshid, E, Altmann, K.H, Locher, K.P, Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Zechner, M. | | Deposit date: | 2023-08-16 | | Release date: | 2024-11-06 | | Last modified: | 2024-11-27 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Modulation of ABCG2 Transporter Activity by Ko143 Derivatives.
Acs Chem.Biol., 19, 2024
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5NJG
 | | Structure of an ABC transporter: part of the structure that could be built de novo | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | | Authors: | Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P. | | Deposit date: | 2017-03-28 | | Release date: | 2017-06-07 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
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6HZM
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium (alternative placement of Magnesium into the cryo-EM density) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | | Authors: | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | Deposit date: | 2018-10-23 | | Release date: | 2018-11-14 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
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6HBU
 | | Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | | Authors: | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | | Deposit date: | 2018-08-13 | | Release date: | 2018-11-07 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
Nature, 563, 2018
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