6HIJ
Cryo-EM structure of the human ABCG2-MZ29-Fab complex with cholesterol and PE lipids docked
Summary for 6HIJ
Entry DOI | 10.2210/pdb6hij/pdb |
Related | 6FFC |
EMDB information | 4256 4256 |
Descriptor | ATP-binding cassette sub-family G member 2, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, CHOLESTEROL, ... (4 entities in total) |
Functional Keywords | abc transporter, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 155678.16 |
Authors | Jackson, S.M.,Manolaridis, I.,Kowal, J.,Zechner, M.,Taylor, N.M.I.,Bause, M.,Bauer, S.,Bartholomaeus, R.,Stahlberg, H.,Bernhardt, G.,Koenig, B.,Buschauer, A.,Altmann, K.H.,Locher, K.P. (deposition date: 2018-08-30, release date: 2018-09-19, Last modification date: 2019-12-11) |
Primary citation | Jackson, S.M.,Manolaridis, I.,Kowal, J.,Zechner, M.,Taylor, N.M.I.,Bause, M.,Bauer, S.,Bartholomaeus, R.,Bernhardt, G.,Koenig, B.,Buschauer, A.,Stahlberg, H.,Altmann, K.H.,Locher, K.P. Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat.Struct.Mol.Biol., 25:333-340, 2018 Cited by PubMed: 29610494DOI: 10.1038/s41594-018-0049-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.56 Å) |
Structure validation
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