7OJ8
ABCG2 E1S turnover-2 state
Summary for 7OJ8
Entry DOI | 10.2210/pdb7oj8/pdb |
EMDB information | 12939 |
Descriptor | Broad substrate specificity ATP-binding cassette transporter ABCG2, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... (4 entities in total) |
Functional Keywords | abc transporter plasma membrane atp multidrug resistance, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 149965.28 |
Authors | Ni, D.,Yu, Q.,Kowal, J.,Manolaridis, I.,Jackson, S.M.,Stahlberg, H.,Locher, K.P. (deposition date: 2021-05-14, release date: 2021-07-21, Last modification date: 2021-07-28) |
Primary citation | Yu, Q.,Ni, D.,Kowal, J.,Manolaridis, I.,Jackson, S.M.,Stahlberg, H.,Locher, K.P. Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12:4376-4376, 2021 Cited by PubMed: 34282134DOI: 10.1038/s41467-021-24651-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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