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7OJ8

ABCG2 E1S turnover-2 state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Broad substrate specificity ATP-binding cassette transporter ABCG2polymer66573526.92UniProt (Q9UNQ0)
Pfam (PF00005)
Pfam (PF19055)
Pfam (PF01061)
Homo sapiens (Human)ATP-binding cassette sub-family G member 2,Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter
2C, F
(A, B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
3D, E, H, I
(A, B)
CHOLESTEROLnon-polymer386.74Chemie (CLR)
4G
(B)
estrone 3-sulfatenon-polymer350.41Chemie (FY5)
Sequence modifications
A, B: 2 - 655 (UniProt: Q9UNQ0)
PDBExternal DatabaseDetails
Met -9-initiating methionine
Asp -8-expression tag
Tyr -7-expression tag
Lys -6-expression tag
Asp -5-expression tag
Asp -4-expression tag
Asp -3-expression tag
Asp -2-expression tag
Lys -1-expression tag
Gly 0-expression tag
Ser 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight147053.9
Non-Polymers*Number of molecules7
Total formula weight2911.4
All*Total formula weight149965.3
*Water molecules are not included.

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PDB entries from 2025-10-22

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