5XG0
 
 | | Crystal structure of a novel PET hydrolase from Ideonella sakaiensis 201-F6 | | Descriptor: | Poly(ethylene terephthalate) hydrolase | | Authors: | Han, X, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T. | | Deposit date: | 2017-04-11 | | Release date: | 2017-12-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structural insight into catalytic mechanism of PET hydrolase
Nat Commun, 8, 2017
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7CQB
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4MH1
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4LSW
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7X1Z
 | | Structure of the phosphorylation-site double mutant S431E/T432E of the KaiC circadian clock protein | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION | | Authors: | Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q. | | Deposit date: | 2022-02-25 | | Release date: | 2023-04-19 | | Last modified: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex
Nat Commun, 14, 2023
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7X1Y
 | | Structure of the phosphorylation-site double mutant S431A/T432A of the KaiC circadian clock protein | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION | | Authors: | Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q. | | Deposit date: | 2022-02-25 | | Release date: | 2023-04-26 | | Last modified: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex
Nat Commun, 14, 2023
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4QQR
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4Y4N
 | | Thiazole synthase Thi4 from Methanococcus igneus | | Descriptor: | 2-[(E)-[(4R)-5-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-3-oxidanylidene-pentan-2-ylidene]amino]ethanoic acid, FE (II) ION, Putative ribose 1,5-bisphosphate isomerase | | Authors: | Zhang, X, Ealick, S.E. | | Deposit date: | 2015-02-10 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases.
Biochemistry, 55, 2016
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4Y4M
 | | Thiazole synthase Thi4 from Methanocaldococcus jannaschii | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Putative ribose 1,5-bisphosphate isomerase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R)-2,3,5-tris(oxidanyl)-4-oxidanylidene-pentyl] hydrogen phosphate | | Authors: | Zhang, X, Ealick, S.E. | | Deposit date: | 2015-02-10 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases.
Biochemistry, 55, 2016
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4Y4L
 | | Crystal structure of yeast Thi4-C205S | | Descriptor: | (2E)-2-[(2S,4R)-5-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-3-oxidanylidene-pentan-2-yl]iminoethanoic acid, Thiamine thiazole synthase | | Authors: | Zhang, X, Ealick, S.E. | | Deposit date: | 2015-02-10 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases.
Biochemistry, 55, 2016
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8T3V
 | | Cryo-EM structure of the DHA bound FFA1-Gq complex | | Descriptor: | CHOLESTEROL, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 1, ... | | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | Deposit date: | 2023-06-07 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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8SG1
 | | Cryo-EM structure of CMKLR1 signaling complex | | Descriptor: | CHOLESTEROL, Chemerin 9, Chemerin-like receptor 1, ... | | Authors: | Zhang, X, Zhang, C. | | Deposit date: | 2023-04-11 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural basis of G protein-Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist.
Plos Biol., 21, 2023
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1PEG
 | | Structural basis for the product specificity of histone lysine methyltransferases | | Descriptor: | Histone H3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | | Authors: | Zhang, X, Yang, Z, Khan, S.I, Horton, J.R, Tamaru, H, Selker, E.U, Cheng, X. | | Deposit date: | 2003-05-21 | | Release date: | 2003-08-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structural basis for the product specificity of histone lysine methyltransferases
Mol.Cell, 12, 2003
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8T3Q
 | | Cryo-EM structure of the DHA bound FFA4-Gq complex | | Descriptor: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | Deposit date: | 2023-06-07 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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8T3O
 | | Cryo-EM structure of the TUG-891 bound FFA4-Gq complex | | Descriptor: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, ... | | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | Deposit date: | 2023-06-07 | | Release date: | 2024-01-17 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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8T3S
 | | Cryo-EM structure of the Butyrate bound FFA2-Gq complex | | Descriptor: | CHOLESTEROL, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | Deposit date: | 2023-06-07 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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1ML9
 | | Structure of the Neurospora SET domain protein DIM-5, a histone lysine methyltransferase | | Descriptor: | Histone H3 methyltransferase DIM-5, UNKNOWN, ZINC ION | | Authors: | Zhang, X, Tamaru, H, Khan, S.I, Horton, J.R, Keefe, L.J, Selker, E.U, Cheng, X. | | Deposit date: | 2002-08-30 | | Release date: | 2002-10-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure of the Neurospora SET domain protein DIM-5,
a histone H3 lysine methyltransferase
Cell(Cambridge,Mass.), 111, 2002
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3JB6
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ... | | Authors: | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | Deposit date: | 2015-08-02 | | Release date: | 2015-10-28 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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3JB7
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | Descriptor: | CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | Deposit date: | 2015-08-03 | | Release date: | 2015-10-28 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (4.001 Å) | | Cite: | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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5T2A
 | | CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution | | Descriptor: | 18S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Zhang, X, Lai, M, Zhou, Z.H. | | Deposit date: | 2016-08-23 | | Release date: | 2017-01-25 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
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5T2C
 | | CryoEM structure of the human ribosome at 3.6 Angstrom resolution | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Zhang, X, Lai, M, Zhou, Z.H. | | Deposit date: | 2016-08-23 | | Release date: | 2017-01-25 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
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8HMY
 | | Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex | | Descriptor: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | Authors: | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | Deposit date: | 2022-12-06 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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8HMZ
 | | Cryo-EM structure of the human post-catalytic TSEN/pre-tRNA complex | | Descriptor: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | Authors: | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | Deposit date: | 2022-12-06 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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7MDO
 | | Structure of human p97 ATPase L464P mutant | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | Authors: | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | | Deposit date: | 2021-04-05 | | Release date: | 2021-08-25 | | Last modified: | 2021-09-22 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.
Biochem.J., 478, 2021
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7MDM
 | | Structure of human p97 ATPase L464P mutant | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | Authors: | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | | Deposit date: | 2021-04-05 | | Release date: | 2021-08-25 | | Last modified: | 2021-09-22 | | Method: | ELECTRON MICROSCOPY (4.86 Å) | | Cite: | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.
Biochem.J., 478, 2021
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