8T3Q

Cryo-EM structure of the DHA bound FFA4-Gq complex

Summary for 8T3Q

Entry DOI	10.2210/pdb8t3q/pdb
EMDB information	41008
Descriptor	Guanine nucleotide-binding protein G(q), Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, ... (6 entities in total)
Functional Keywords	gpcr, agonist, membrane protein
Biological source	Homo sapiens More
Total number of polymer chains	5
Total formula weight	134082.21
Authors	Zhang, X.,Tikhonova, I.,Milligan, G.,Zhang, C. (deposition date: 2023-06-07, release date: 2024-01-24)
Primary citation	Zhang, X.,Guseinov, A.A.,Jenkins, L.,Li, K.,Tikhonova, I.G.,Milligan, G.,Zhang, C. Structural basis for the ligand recognition and signaling of free fatty acid receptors. Sci Adv, 10:eadj2384-eadj2384, 2024 Cited by PubMed: 38198545 DOI: 10.1126/sciadv.adj2384 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.14 Å)

Structure validation