8T3Q
Cryo-EM structure of the DHA bound FFA4-Gq complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) | polymer | 230 | 26670.3 | 1 | Homo sapiens | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 342 | 37516.9 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (N) | scFv16 | polymer | 266 | 28634.8 | 1 | Mus musculus | ||
| 4 | D (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 57 | 6261.2 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (R) | Free fatty acid receptor 4 | polymer | 308 | 34670.5 | 1 | UniProt (Q5NUL3) Pfam (PF00001) | Homo sapiens (human) | G-protein coupled receptor 120,G-protein coupled receptor 129,G-protein coupled receptor GT01,G-protein coupled receptor PGR4,Omega-3 fatty acid receptor 1 |
| 6 | F (R) | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID | non-polymer | 328.5 | 1 | Chemie (HXA) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Gly 341 | - | expression tag |
| Ser 342 | - | expression tag |
| Ser 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 133753.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 328.5 | |
| All* | Total formula weight | 134082.2 |
