7MDM

Structure of human p97 ATPase L464P mutant

Summary for 7MDM

• Entry DOI: 10.2210/pdb7mdm/pdb
• EMDB information: 23775
• Descriptor: Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE (2 entities in total)
• Functional Keywords: motor protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 539087.84

Authors

Zhang, X.,Gui, L.,Li, S.,Nandi, P.,Columbres, R.C.,Wong, D.E.,Moen, D.R.,Lin, H.J.,Chiu, P.-L.,Chou, T.-F. (deposition date: 2021-04-05, release date: 2021-08-25, Last modification date: 2021-09-22)

• Primary citation: Zhang, X.,Gui, L.,Li, S.,Nandi, P.,Columbres, R.C.,Wong, D.E.,Moen, D.R.,Lin, H.J.,Chiu, P.L.,Chou, T.F.; Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.; Biochem.J., 478:3185-3204, 2021; PubMed: 34405853; DOI: 10.1042/BCJ20210288

Experimental method

ELECTRON MICROSCOPY (4.86 Å)