8T3S

Cryo-EM structure of the Butyrate bound FFA2-Gq complex

Summary for 8T3S

• Entry DOI: 10.2210/pdb8t3s/pdb
• EMDB information: 41010
• Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: gpcr, agonist, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 125960.33

Authors

Zhang, X.,Tikhonova, I.,Milligan, G.,Zhang, C. (deposition date: 2023-06-07, release date: 2024-01-24)

• Primary citation: Zhang, X.,Guseinov, A.A.,Jenkins, L.,Li, K.,Tikhonova, I.G.,Milligan, G.,Zhang, C.; Structural basis for the ligand recognition and signaling of free fatty acid receptors.; Sci Adv, 10:eadj2384-eadj2384, 2024; PubMed: 38198545; DOI: 10.1126/sciadv.adj2384

Experimental method

ELECTRON MICROSCOPY (3.07 Å)