8T3S
Cryo-EM structure of the Butyrate bound FFA2-Gq complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 230 | 26670.3 | 1 | Homo sapiens | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 342 | 37516.9 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 57 | 6261.2 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (N) | scFv16 | polymer | 232 | 25331.4 | 1 | Mus musculus | ||
| 5 | E (R) | Free fatty acid receptor 2 | polymer | 258 | 29192.8 | 1 | Pfam (PF00001) UniProt (by SIFTS) (O15552) | Homo sapiens | |
| 6 | F (R) | butanoic acid | non-polymer | 88.1 | 1 | Chemie (BUA) | |||
| 7 | G (R) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
| 8 | H, I (R) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Gly 341 | - | expression tag |
| Ser 342 | - | expression tag |
| Ser 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 124972.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 987.6 | |
| All* | Total formula weight | 125960.3 |
