8T3V
Cryo-EM structure of the DHA bound FFA1-Gq complex
Summary for 8T3V
Entry DOI | 10.2210/pdb8t3v/pdb |
EMDB information | 41013 |
Descriptor | Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, agonist, membrane protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 129092.80 |
Authors | Zhang, X.,Tikhonova, I.,Milligan, G.,Zhang, C. (deposition date: 2023-06-07, release date: 2024-01-24) |
Primary citation | Zhang, X.,Guseinov, A.A.,Jenkins, L.,Li, K.,Tikhonova, I.G.,Milligan, G.,Zhang, C. Structural basis for the ligand recognition and signaling of free fatty acid receptors. Sci Adv, 10:eadj2384-eadj2384, 2024 Cited by PubMed: 38198545DOI: 10.1126/sciadv.adj2384 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.39 Å) |
Structure validation
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